Department of Paediatric and Child Health, Faculty of Medicine, Lira University, Lira, Uganda.
Paediatric Oncology Service, Uganda Cancer Institute, Kampala, Uganda.
J Adolesc Young Adult Oncol. 2024 Aug;13(4):629-636. doi: 10.1089/jayao.2023.0184. Epub 2024 Apr 5.
Reproductive health (RH) is a critical issue among cancer survivors worldwide. However, in developing countries where RH services for patients with cancer are often lacking, reproductive concerns among adolescent and young adult (AYA) survivors remain uncertain. In this study, we assessed the reproductive concerns of AYA cancer survivors in a resource-limited context of Uganda. We collected data from AYA cancer survivors at two facilities in Uganda using an interviewer-administered questionnaire. Descriptive statistics were calculated, one-way analysis of variance was used for intergroup comparisons, and multiple regressions were used to test for predictors of reproductive concerns. A total of 110 AYA cancer survivors, with a median age of 20 years (interquartile range [IQR], 18-22), were interviewed. More than half (53.6%) of the respondents were males. The median time since cancer diagnosis was 19 months (IQR, 13.0-35.0). Almost all (91.8%) respondents had a future desire to have children, but only 15.5% received reproductive counseling. The mean total score for the reproductive concern subscales was highest for the fertility concern, followed by the information-seeking and health-related concerns. Reproductive counseling, desire to have children, and respondents' age were the factors influencing reproductive concern. The study shows a strong desire for biological parenthood with very low reproductive counseling among AYA cancer survivors, who remain concerned about their fertility, information needs, and health. This outcome underscores the need to integrate RH services into resource-limited cancer care settings.
生殖健康(RH)是全球癌症幸存者面临的一个关键问题。然而,在癌症患者 RH 服务往往匮乏的发展中国家,青少年和年轻成人(AYA)幸存者的生殖问题仍然不确定。在这项研究中,我们评估了乌干达资源有限环境中 AYA 癌症幸存者的生殖关注。我们使用访谈者管理的问卷从乌干达的两个设施中收集了 AYA 癌症幸存者的数据。计算了描述性统计数据,使用单因素方差分析进行了组间比较,使用多元回归测试了生殖关注的预测因素。共采访了 110 名 AYA 癌症幸存者,中位年龄为 20 岁(四分位距 [IQR],18-22)。超过一半(53.6%)的受访者为男性。癌症诊断后的中位时间为 19 个月(IQR,13.0-35.0)。几乎所有(91.8%)的受访者都希望将来有孩子,但只有 15.5%接受了生殖咨询。生殖关注子量表的平均总分以生育关注最高,其次是信息寻求和健康相关的关注。生殖咨询、生育意愿和受访者年龄是影响生殖关注的因素。该研究表明,AYA 癌症幸存者强烈希望拥有生物学上的子女,但接受的生殖咨询却非常少,他们仍然关注自己的生育能力、信息需求和健康。这一结果突显了在资源有限的癌症护理环境中整合 RH 服务的必要性。