Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Headache. 2024 Apr;64(4):390-399. doi: 10.1111/head.14708. Epub 2024 Apr 6.
To evaluate pain medication beliefs in a community sample of individuals with headache.
Previous studies of medication adherence for individuals with headache have identified a high rate of prescription nonfulfillment, frequent medication discontinuation, and widely varying levels of medication-related satisfaction. Still, there is a limited understanding of how these individuals view their medications and their relationships with health-care providers. Insight into these perceptions could prove useful in explaining medication adherence behaviors.
In this secondary analysis of a cross-sectional study, data from N = 215 adults with headache were analyzed. Participants completed the Pain Medication Attitudes Questionnaire (PMAQ), Center for Epidemiologic Studies Depression Scale (CES-D), State-Trait Anxiety Inventory Form Y-2, Weekly Stress Inventory Short Form, and Migraine Disability Scale. These participants also provided a list of their current pain medications.
Using the PMAQ, participants could be characterized as having medication beliefs that were "trusting and unconcerned" (n = 83/215 [38.6%]), "skeptical and somewhat worried" (n = 99/215 [46.0%]), or "skeptical and concerned" (n = 33/215 [15.3%]). Individuals with skeptical and concerned beliefs expressed elevated concerns (z > 1.15) about side effects, scrutiny, perceived need, tolerance, withdrawal, and addiction. Individuals who were trusting and unconcerned expressed low levels (z < -0.40) of these beliefs. Increasing levels of mistrust and medication concerns were correlated with higher depression scores on the CES-D, with values ranging from r = 0.23 to r = 0.38.
Subgroups of pain medication beliefs were identified, including two groups of patients with at least some concerns about their medical providers. Beliefs ranged from a lack of concern about using pain medications to worries about scrutiny and harm. It is unclear if poor experiences with pain medications cause these beliefs or if they prevent individuals from effectively utilizing medications. Additionally, more negative beliefs about pain medications were associated with more depressive symptoms.
评估社区头痛患者群体中对疼痛药物的信念。
既往针对头痛患者药物依从性的研究已确定,存在较高的处方未完成率、频繁停药以及药物相关满意度差异较大等情况。然而,对于这些个体如何看待自身药物及与医疗保健提供者的关系,我们仍知之甚少。了解这些认知可能有助于解释药物依从行为。
在这项横断面研究的二次分析中,对 215 名患有头痛的成年人的数据进行了分析。参与者完成了疼痛药物态度问卷(PMAQ)、流行病学研究中心抑郁量表(CES-D)、状态-特质焦虑量表 Y-2 型、每周压力量表短表和偏头痛残疾量表。这些参与者还提供了他们目前使用的疼痛药物清单。
根据 PMAQ,参与者的药物信念可分为“信任且不担忧”(n = 83/215 [38.6%])、“怀疑且有些担忧”(n = 99/215 [46.0%])或“怀疑且担忧”(n = 33/215 [15.3%])。持怀疑和担忧态度的个体表达了对副作用、审查、感知需求、耐受性、戒断和成瘾的更高担忧(z > 1.15)。信任且不担忧的个体表达了较低的此类信念(z < -0.40)。对不信任和药物担忧程度的增加与 CES-D 上更高的抑郁评分相关,其值范围从 r = 0.23 到 r = 0.38。
确定了疼痛药物信念的亚组,包括至少对医疗提供者有一些担忧的两类患者。信念范围从对使用疼痛药物缺乏关注到对审查和伤害的担忧。目前尚不清楚是对疼痛药物的不良体验导致了这些信念,还是它们阻止了个体有效利用药物。此外,对疼痛药物的负面信念越多,抑郁症状越严重。