Videnza Consultores, Videnza, Lima, Perú.
Health Economics & Value Assesment, Sanofi, Bogotá, Colombia.
Expert Rev Pharmacoecon Outcomes Res. 2024 Jun;24(5):661-669. doi: 10.1080/14737167.2024.2333337. Epub 2024 Apr 8.
Type 2 diabetes mellitus (T2DM) represents an increasing public health problem in Peru. This study aims to estimate the national economic burden of this disease for the public funder, the social security, and private sector insurers.
Direct healthcare costs were estimated for a cohort of 45-to-75-year-old adults diagnosed with T2DM in 2019, over a 20-year period. Disease progression was modeled using PROSIT Models and literature, including acute and chronic microvascular and macrovascular complications. Three scenarios of glycemic control were considered: current levels of 35.8% of the population controlled (HbA1c < 7%) (S1); 100% controlled (S2) and; 100% uncontrolled (S3). The impact of diabetes prevalence on overall costs was evaluated in sensitivity analysis.
Total national economic burden was estimated at $15,405,448,731; an annual average per patient of $2,158. Total costs would decrease to $12,853,113,596 (-16.6%) in S2 and increase to $16,828,713,495 (+9.2%) in S3. Treating patients with complications and risk factors could cost 6.5 times more, being stroke the complication with the highest impact. Up to a 67.6% increase in total costs was found when increasing T2DM prevalence.
T2DM places a heavy burden on the Peruvian healthcare budget that will be even greater if poor glycemic control is maintained.
2 型糖尿病(T2DM)在秘鲁是一个日益严重的公共卫生问题。本研究旨在为公共资金提供者、社会保障和私营部门保险公司估算该疾病的国家经济负担。
在 2019 年,对 45-75 岁患有 T2DM 的成年人队列进行了为期 20 年的直接医疗成本估算。使用 PROSIT 模型和文献中的数据对疾病进展进行建模,包括急性和慢性微血管和大血管并发症。考虑了三种血糖控制情景:当前有 35.8%的人群控制率(HbA1c<7%)(S1);100%控制率(S2);100%未控制率(S3)。在敏感性分析中评估了糖尿病患病率对总费用的影响。
全国经济总负担估计为 1540.5448731 亿美元;每名患者的年均费用为 2158 美元。在 S2 中,总费用将降至 1285.3113596 亿美元(-16.6%),在 S3 中,总费用将增至 1682.8713495 亿美元(+9.2%)。治疗并发症和危险因素患者的费用可能会增加 6.5 倍,中风是影响最大的并发症。当 T2DM 患病率增加时,总费用增加了 67.6%。
T2DM 给秘鲁的医疗保健预算带来了沉重的负担,如果血糖控制不佳,这一负担还会更大。