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吲哚菁绿荧光引导下的膝关节镜检查:一项用于研究半月板周围微血管系统的技术说明

Indocyanine Green Fluorescence-Guided Knee Arthroscopy: A Technical Note for Investigating the Microvasculature Around the Meniscus.

作者信息

Kamimura Tamiko

机构信息

Department of Orthopaedic Surgery, Tokorozawa Chuo Hospital, Tokorozawa, Saitama, Japan.

出版信息

Arthrosc Tech. 2024 Jan 1;13(3):102878. doi: 10.1016/j.eats.2023.11.006. eCollection 2024 Mar.

Abstract

Vascularity of the meniscus is the most important key to meniscal tear healing. However, blood supply to the meniscus is limited to approximately the outer 10% to 25% of the meniscus, known as the "red-red zone." The cyanine dye indocyanine green (ICG) is commonly used as a contrast imaging agent for visualizing vascularity in several medical fields. Moreover, ICG fluorescence-guided surgery is a modern trend in the field of laparoscopic surgery in which the characteristic of fluorescence enhancement under a near-infrared light is used. However, ICG fluorescence-guided knee arthroscopy findings remain unknown. In this Technical Note, the author applied ICG fluorescence-guided surgery to knee arthroscopy to evaluate blood supply to the meniscus and intra-articular apparatus. Additionally, the arthroscopic findings of ICG fluorescence-guided knee arthroscopy for degenerative tears of the medial meniscus before and after meniscal repair are presented. Through the intravenous injection of ICG solution, real-time detection of fluorescence may contribute to investigating case-specific vascularization of the meniscus during arthroscopy in the next generation.

摘要

半月板的血管分布是半月板撕裂愈合的最重要关键因素。然而,半月板的血液供应仅限于半月板外侧约10%至25%的区域,即所谓的“红-红区”。菁染料吲哚菁绿(ICG)通常用作对比成像剂,用于在多个医学领域可视化血管分布。此外,ICG荧光引导手术是腹腔镜手术领域的一种现代趋势,其利用了近红外光下荧光增强的特性。然而,ICG荧光引导膝关节镜检查的结果尚不清楚。在本技术说明中,作者将ICG荧光引导手术应用于膝关节镜检查,以评估半月板和关节内结构的血液供应。此外,还展示了ICG荧光引导膝关节镜检查对内侧半月板退变撕裂在半月板修复前后的关节镜检查结果。通过静脉注射ICG溶液,荧光的实时检测可能有助于在下一代关节镜检查期间研究特定病例的半月板血管化情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ac5/10995639/ea1ee4922bc2/gr1.jpg

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