PET-CT引导下立体定向放射治疗联合帕博利珠单抗治疗多形性肺上沟瘤的持久完全缓解：病例报告及文献综述
Durable complete response to PET-CT driven stereotactic radiation therapy plus pembrolizumab for pleomorphic Pancoast cancer: Case report and literature review.
作者信息
Castelluccia Alessandra, Sardaro Angela, Niccoli Asabella Artor, Pisani Antonio Rosario, Rubini Dino, Portaluri Maurizio, Tramacere Francesco
机构信息
Department of Radiotherapy "A. Perrino" Hospital Brindisi Italy.
Section of Radiology and Radiation Oncology, Interdisciplinary Department of Medicine University of Bari "Aldo Moro" Bari Italy.
出版信息
Clin Case Rep. 2024 Apr 5;12(4):e8633. doi: 10.1002/ccr3.8633. eCollection 2024 Apr.
PET-driven SBRT plus pembrolizumab as first-line therapy against pleomorphic Pancoast cancer appears beneficial, probably due to high equivalent doses of SBRT on photopenic necrotic core and synergic immune system stimulation of immunoradiotherapy.
正电子发射断层扫描（PET）引导下的立体定向体部放疗（SBRT）联合帕博利珠单抗作为一线治疗多形性肺上沟癌似乎有益，这可能是由于SBRT在放射性坏死核心上的等效剂量较高以及免疫放疗对免疫系统的协同刺激作用。
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