Forzano Imma, Santulli Gaetano
Department of Advanced Biomedical Sciences, Division of Cardiology, "Federico II" University, International Translational Research and Medical Education (ITME) Consortium, Academic Research Unit, 80131, Naples, Italy.
Department of Medicine (Division of Cardiology), Wilf Family Cardiovascular Research Institute, Albert Einstein College of Medicine, New York City, 10461, NY.
Top Ital Sci J. 2024 Mar;1(2). doi: 10.62684/DMFZ6956. Epub 2024 Mar 5.
Patent Foramen Ovale (PFO) is a remnant of fetal circulation that could be observed in the 25% of the population worldwide. PFO is associated to numerous clinical conditions as migraines, coronary embolization, transient ischemic attacks, and stroke. The main PFO concerns are related to its correlation to stroke, in particular in young adults. Despite the impact on morbidity that PFO could have, to date there is not clear evidence about its management and treatment. In this narrative review our aim is to summarize the more recent evidence in the literature dealing with PFO, in order to provide an updated overview on this topic.
卵圆孔未闭（PFO）是胎儿循环的残留物，全球25%的人口中可观察到。PFO与多种临床病症相关，如偏头痛、冠状动脉栓塞、短暂性脑缺血发作和中风。PFO主要关注点与其和中风的关联有关，尤其是在年轻人中。尽管PFO可能对发病率有影响，但迄今为止，关于其管理和治疗尚无明确证据。在这篇叙述性综述中，我们的目的是总结文献中关于PFO的最新证据，以便提供关于该主题的最新概述。
