Dosani Aliyah, Sikdar Khokan C, Kumaran Mahalakshmi, Kumaran Kumar, Hyderi Abbas, Benlamri Amina, Rai Baldeep, Singhal Nalini, Lodha Abhay
Faculty of Health, Community and Education, School of Nursing and Midwifery, Mount Royal University, Calgary, Alberta, Canada.
Department of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Paediatr Child Health. 2023 Sep 7;29(2):90-97. doi: 10.1093/pch/pxad063. eCollection 2024 May.
The objective of this study was to determine if the COVID-19 pandemic impacted different types of preterm birth rates in Alberta, Canada.
A population-based, retrospective, cohort study was conducted from March 15, 2015 to December 31, 2020 using provincial data. The primary exposure was the COVID-19 lockdown period, and the primary outcome was the incidence of preterm birth (<37 weeks gestational age). Multivariable analyses in the complete lockdown and overall lockdown (partial and complete lockdown) periods were performed to test the association between the year of birth and preterm birth status and were adjusted for various independent variables. Preterm birth status was adjusted for various confounding factors.
Following the analysis of n = 41,187 mothers and their singleton infants, we found that the lockdown due to COVID-19 had no impact in reducing the overall preterm birth rate. However, a paradoxical influence was observed with an increase of extremely low preterm births in the overall lockdown period, and a decrease in moderate preterm births during the complete lockdown period.
The results of this study demonstrated that there was a decrease in moderate and increase in extremely low preterm birth rates as a result of the COVID-19 lockdown. However, the COVID-19 lockdown did not impact the very preterm and late preterm birth rate in Alberta.
本研究的目的是确定新冠疫情是否对加拿大艾伯塔省不同类型的早产率产生影响。
利用省级数据，于2015年3月15日至2020年12月31日开展了一项基于人群的回顾性队列研究。主要暴露因素为新冠疫情封锁期，主要结局为早产（孕周<37周）的发生率。在完全封锁期和总体封锁期（部分封锁和完全封锁）进行多变量分析，以检验出生年份与早产状态之间的关联，并对各种独立变量进行了调整。对早产状态进行了各种混杂因素的调整。
在对41187名母亲及其单胎婴儿进行分析后，我们发现，新冠疫情导致的封锁对降低总体早产率没有影响。然而，在总体封锁期观察到一种矛盾的影响，即极低早产率增加，而在完全封锁期中度早产率下降。
本研究结果表明，新冠疫情封锁导致中度早产率下降，极低早产率上升。然而，新冠疫情封锁并未影响艾伯塔省的极早产和晚期早产率。
