Nuclear Medicine Unit, Imaging Department, IRCCS Bambino Gesù Children's Hospital, Rome, Italy -
Nuclear Medicine Unit, Imaging Department, IRCCS Bambino Gesù Children's Hospital, Rome, Italy.
Q J Nucl Med Mol Imaging. 2024 Mar;68(1):23-31. doi: 10.23736/S1824-4785.24.03548-9.
Pediatric gastrointestinal imaging plays a crucial role in evaluating and managing digestive system disorders in children. This comprehensive review dives into the nuances of pediatric gastrointestinal imaging techniques, focusing on three specific modalities: gastric emptying scintigraphy (GES), intestinal transit scintigraphy (ITS), and gastrointestinal bleeding scintigraphy. GES involves real-time monitoring of stomach emptying using radiotracers and gamma camera technology. While challenges exist in standardizing protocols due to age-specific meal compositions, GES remains pivotal in diagnosing motility disorders, gastroesophageal reflux, and abdominal pain in children. ITS, utilizing [Ga], provides insights into gastrointestinal motility disorders such as Hirschsprung disease. It aids in whole-gut transit evaluation, guiding surgical interventions and improving long-term clinical outcomes. Gastrointestinal bleeding scintigraphy, employing [mTc], assists in diagnosing conditions like Meckel's diverticulum and occult bleeding, offering continuous monitoring to pinpoint the bleeding site along the entire gastrointestinal tract. SPECT-CT improves the accuracy and the standards of care. Each technique's protocol details, clinical indications, and diagnostic capabilities are thoroughly discussed, highlighting the importance of these non-invasive, functional imaging modalities in pediatric gastroenterology.
儿科胃肠影像学在评估和治疗儿童消化系统疾病方面发挥着关键作用。本综述深入探讨了儿科胃肠影像学技术的细微差别,重点介绍了三种特定的模式:胃排空闪烁显像(GES)、肠道通过闪烁显像(ITS)和胃肠道出血闪烁显像。GES 涉及使用放射性示踪剂和伽马相机技术实时监测胃排空。尽管由于特定年龄的膳食组成使标准化方案存在挑战,但 GES 仍然是诊断儿童动力障碍、胃食管反流和腹痛的关键。ITS 利用 [Ga] 提供有关胃肠道动力障碍的信息,如先天性巨结肠。它有助于全肠道通过评估,指导手术干预并改善长期临床结果。胃肠道出血闪烁显像采用 [mTc] 有助于诊断梅克尔憩室和隐性出血等病症,提供连续监测以确定整个胃肠道的出血部位。SPECT-CT 提高了准确性和护理标准。详细讨论了每种技术的方案细节、临床适应证和诊断能力,强调了这些非侵入性、功能性影像学模式在儿科胃肠病学中的重要性。