Prusty Nilamadhab, Peela Sai Y, Manaf Haifa, Thakkar Smit, Yanamadala Yaswanthi, Shashank Chapala
Department of ENT, FM Medical College, Balasore, Odisha, India.
MBBS, Andhra Medical College, Visakhapatnam, Andhra Pradesh, India.
J Pharm Bioallied Sci. 2024 Feb;16(Suppl 1):S293-S295. doi: 10.4103/jpbs.jpbs_497_23. Epub 2024 Feb 29.
The impact that vitamin D (vit D) has on a variety of medical conditions like diabetes, cardiovascular, oncological, and central nervous system disorders has been a topic of interest for many years now. It is well-known that vit D deficiency is substantially more common in epileptics than in healthy subjects. The current research was piloted to analyse the vit D levels of the blood in newborns with seizures, as well as mothers' vit D status included subjects.
A cross-sectional examination was piloted at a tertiary care center, which had a (NICU). The subjects were neonates and their mothers. The levels of vit D were measured in term and late preterm newborns who had been brought to the NICU with convulsions. Term or late preterm infants who were healthy and hospitalized in the same hospital's postnatal unit as their mothers served as the controls for the study. Demographics, as well as the vit D levels of both the neonate and the mother, were estimated and compared and evaluated for any significance, keeping significance at less than 0.05.
Of the 72 neonates included, they were similarly distributed between the epileptic (37) and healthy subjects. (40) The mothersy subjects.cluded, they were sim D levels averaged 15.11 ded, they were similarly distributed b D levels of their newborns were 13.26 ± 5.12 ng/mL ( = 0.77). There was no significant variance between the healthy and epileptic neonates ( = 0.212).
The current studyficant variance between the healthy and epileptic neonates (eptic with convulsions. Termserum vit D levels and epileptic activity in neonates. Nevertheless, the levels of the vitamin were < 20 ng/mL among all the neonates. Interventions to improve the vit D levels have to be implemented.
多年来,维生素D(vit D)对多种疾病如糖尿病、心血管疾病、肿瘤疾病和中枢神经系统疾病的影响一直是人们关注的话题。众所周知,癫痫患者中vit D缺乏的情况比健康受试者更为普遍。当前的研究旨在分析癫痫发作新生儿的血液中vit D水平,以及母亲的vit D状况(纳入研究对象)。
在一家设有新生儿重症监护病房(NICU)的三级护理中心进行了一项横断面检查。研究对象为新生儿及其母亲。对因惊厥被送至NICU的足月儿和晚期早产儿的vit D水平进行了测量。在同一家医院产后病房与母亲一起住院的健康足月儿或晚期早产儿作为研究对照。估算并比较了人口统计学数据以及新生儿和母亲的vit D水平,并评估其是否具有任何显著性差异,显著性水平设定为小于0.05。
在纳入的72名新生儿中,癫痫患儿(37名)和健康受试者(40名)分布相似。母亲的vit D水平平均为15.11 ng/mL,其新生儿的vit D水平为13.26±5.12 ng/mL(r = 0.77)。健康新生儿和癫痫新生儿之间无显著差异(p = 0.212)。
当前研究表明健康新生儿和癫痫新生儿之间无显著差异。然而,所有新生儿的维生素水平均<20 ng/mL。必须实施提高vit D水平的干预措施。