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即时血糖仪检测马低血糖的精准度和准确度。

Precision and accuracy of a point of care glucometer for detection of hypoglycaemia in horses.

机构信息

School of Agricultural, Environmental and Veterinary Sciences, Charles Sturt University, Locked Bag 588, Boorooma Street, Wagga Wagga, NSW 2678, Australia.

School of Agricultural, Environmental and Veterinary Sciences, Charles Sturt University, Locked Bag 588, Boorooma Street, Wagga Wagga, NSW 2678, Australia.

出版信息

Vet J. 2024 Jun;305:106109. doi: 10.1016/j.tvjl.2024.106109. Epub 2024 Apr 9.

Abstract

Point-of-care (POC) glucometry is commonly used in horses; however, measurement error with this method when analysing hypoglycaemic samples (<4 mmol/L) is unknown. The objective of this study was to determine the precision and accuracy of glucometry in hypoglycaemic horses in comparison to a laboratory method of glucose measurement (LAB). Repeatability coefficients were 0.47 mmol/L for POC and 0.09 mmol/L for LAB, and coefficients of variation were 10 % and 2.11 %, for the POC and LAB methods, respectively. Systemic bias with the POC method was present, with a mean bias of -0.26 mmol/L (95 % limits of agreement: -0.88 - 0.37) in comparison to LAB, and <70% of measurements were within 20 % of paired LAB results. Prior to use of glucometers, assessment of the diagnostic performance of the equipment is necessary, including determination of acceptable criteria and reference ranges for hypoglycaemic samples.

摘要

即时血糖仪(POC)常用于马匹,但该方法在分析低血糖样本(<4mmol/L)时的测量误差尚不清楚。本研究旨在比较实验室血糖测量方法(LAB),确定 POC 在低血糖马匹中的精密度和准确度。POC 的重复性系数为 0.47mmol/L,LAB 的重复性系数为 0.09mmol/L,POC 和 LAB 方法的变异系数分别为 10%和 2.11%。与 LAB 相比,POC 方法存在系统偏差,平均偏差为-0.26mmol/L(95%一致性界限:-0.88-0.37),<70%的测量值与 LAB 配对结果相差 20%以内。在使用血糖仪之前,需要评估设备的诊断性能,包括确定低血糖样本的可接受标准和参考范围。

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