Özderya Ahmet, Şahin Sinan, Koşmaz Tolga, Maz Mehmet Ali, Yerlikaya Murat Gökhan, Akyüz Ali Rıza, Sayın Muhammet Raşit, Erkan Hakan
Department of Cardiology, Trabzon Kanuni Training and Research Hospital, Trabzon, Turkey.
Department of Cardiology, University of Health Sciences, Şişli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey.
Vascular. 2025 Apr;33(2):253-260. doi: 10.1177/17085381241246905. Epub 2024 Apr 12.
BackgroundThe aim of this study is to investigate the relationship between HALP score and post-contrast acute kidney injury (PC-AKI) and average 6-year mortality in patients undergoing endovascular abdominal aortic aneurysm repair (EVAR).Methods125 patients who underwent EVAR between January 2015 and December 2020 were included in our study. HALP score was calculated with the formula "hemoglobin × albumin × lymphocyte count/platelet count." In the first phase of the study, two groups were developed: those who developed PC-AKI and those who did not. In the second stage, statistical analysis was performed by creating two groups: average 6-year mortality and survivors group.ResultsHALP score was found to be lower in the PC-AKI group [26.12 (14-61.54) versus 40.53 (7.22-103.61); < .001]. Low HALP score was found to be both a dependent and independent predictor of the development of PC-AKI ( = .019). HALP score was also found to be lower in the mortality group compared to the survivors [28.97 (12.6-103.61) versus 40.81 (7.22-99) = .004]. Low HALP score was found to be only a dependent predictor of mortality. The development of PC-AKI was found to be an independent predictor of mortality ( = .042).ConclusionsThe HALP score, which can be calculated with a simple formula, can be used to predict PC-AKI and medium-long-term mortality in EVAR patients.
背景
本研究旨在探讨血管腔内腹主动脉瘤修复术(EVAR)患者中HALP评分与造影剂后急性肾损伤(PC-AKI)及6年平均死亡率之间的关系。
方法
纳入2015年1月至2020年12月期间接受EVAR治疗的125例患者。HALP评分通过“血红蛋白×白蛋白×淋巴细胞计数/血小板计数”公式计算。在研究的第一阶段,分为两组:发生PC-AKI的患者和未发生PC-AKI的患者。在第二阶段,通过将患者分为两组进行统计分析:6年平均死亡率组和存活组。
结果
发现PC-AKI组的HALP评分较低[26.12(14 - 61.54)对40.53(7.22 - 103.61);P <.001]。低HALP评分被发现是PC-AKI发生的依赖和独立预测因素(P =.019)。与存活者相比,死亡率组的HALP评分也较低[28.97(12.6 - 103.61)对40.81(7.22 - 99);P =.004]。低HALP评分被发现只是死亡率的依赖预测因素。PC-AKI的发生被发现是死亡率的独立预测因素(P =.042)。
结论
HALP评分可通过简单公式计算得出,可用于预测EVAR患者的PC-AKI及中长期死亡率。