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子宫平滑肌肿瘤,恶性潜能不确定(STUMP):一例报告

Uterine smooth muscle tumors of uncertain malignant potential (STUMP): A case report.

作者信息

El Hassouni Fatima, Tligui Samia, Lakhdissi Asmaa, Rouas Lamiaa, El Youssfi Mounia

机构信息

Department of Obstetrics and Gynecology, Oncology and High-Risk Pregnancies, Maternity Hospital Souissi, Ibn Sina university Hospital, Rabat, Morocco; Mohamed V University, Rabat, Morocco.

Department of Obstetrics and Gynecology, Oncology and High-Risk Pregnancies, Maternity Hospital Souissi, Ibn Sina university Hospital, Rabat, Morocco; Mohamed V University, Rabat, Morocco.

出版信息

Int J Surg Case Rep. 2024 May;118:109607. doi: 10.1016/j.ijscr.2024.109607. Epub 2024 Apr 4.

Abstract

INTRODUCTION

Uterine smooth muscle tumors of uncertain malignant potential (STUMP) are extremely rare, defined as a uterine smooth muscle tumors that cannot be diagnosed as benign or malignant and does not satisfy all the criteria for leiomyosarcoma or leiomyoma.

CASE REPRESENTATION

A 48-year-old woman who presented with a history of heavy menstrual bleeding and pelvic pain. Physical examination revealed an enlarged uterus. Ultrasonography showed lobular and enlarged uterus containing multiples leiomyomas. A subtotal hysterectomy was performed. A Pathological analysis revealed a uterine mass diagnosed as a smooth muscle tumor of uncertain malignant.

DISCUSSION

Uterine STUMPs are rare and are commonly diagnosed by histopathological evaluation following myomectomy or hysterectomy. The most common clinical manifestations of uterine STUMP are the same as leiomyomas. Prognosis for the patient is unclear and there is a risk of recurrence with the tumors. However, considering their potential risk of recurrence and metastasis, it is advisable to maintain six-monthly controls for 5 years and then annual controls for 5 years more.

CONCLUSION

Due to the rarity of uterine STUMP, there are no specific guidelines for their treatment and control. The scientific literature needs to be constantly updated in order to identify masses suspected of malignancy before surgery and improve patient management and follow-up.

摘要

引言

子宫平滑肌肿瘤,恶性潜能未定(STUMP)极为罕见,定义为无法诊断为良性或恶性且不满足平滑肌肉瘤或平滑肌瘤所有标准的子宫平滑肌肿瘤。

病例报告

一名48岁女性,有月经过多和盆腔疼痛病史。体格检查发现子宫增大。超声检查显示子宫呈小叶状且增大,内有多个平滑肌瘤。行次全子宫切除术。病理分析显示子宫肿块诊断为恶性潜能未定的平滑肌瘤。

讨论

子宫STUMP罕见,通常在肌瘤切除术或子宫切除术后通过组织病理学评估诊断。子宫STUMP最常见的临床表现与平滑肌瘤相同。患者的预后尚不清楚,肿瘤有复发风险。然而,考虑到其潜在的复发和转移风险,建议在5年内每6个月进行一次复查,然后再每年复查5年。

结论

由于子宫STUMP罕见,尚无针对其治疗和监测的具体指南。科学文献需要不断更新,以便在手术前识别疑似恶性的肿块,改善患者管理和随访。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13b8/11024644/07d1f2a20239/gr1.jpg

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