裸盖菇素对共情和亲社会行为的影响：一种关于持久抗抑郁作用的潜在机制。
The effect of psilocybin on empathy and prosocial behavior: a proposed mechanism for enduring antidepressant effects.
作者信息
Bhatt Kush V, Weissman Cory R
机构信息
Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA.
出版信息
Npj Ment Health Res. 2024 Feb 20;3(1):7. doi: 10.1038/s44184-023-00053-8.
Psilocybin is a serotonergic psychedelic shown to have enduring antidepressant effects. Currently, the mechanism for its enduring effects is not well understood. Empathy and prosocial behavior may be important for understanding the therapeutic benefit of psilocybin. In this article we review the effect of psilocybin on empathy and prosocial behavior. Moreover, we propose that psilocybin may induce a positive feedback loop involving empathy and prosocial behavior which helps explain the observed, enduring antidepressant effects.
裸盖菇素是一种血清素能致幻剂，已被证明具有持久的抗抑郁作用。目前，其持久作用的机制尚不清楚。同理心和亲社会行为可能对理解裸盖菇素的治疗益处很重要。在本文中，我们综述了裸盖菇素对同理心和亲社会行为的影响。此外，我们提出裸盖菇素可能会诱导一个涉及同理心和亲社会行为的正反馈回路，这有助于解释所观察到的持久抗抑郁作用。
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