Williamson P M, Smith K V
Clin Exp Neurol. 1978;15:127-30.
Familial polyposis of the colon is associated with an increased incidence in other parts of the body of benign and malignant, soft and hard connective tissue tumours. Clinical details and autopsy findings are reported in a 35-year-old man with familial polyposis who died from reticulum cell sarcoma (microglioma) involving his brain stem and upper spinal cord. While other central nervous system malignancy has been reported in association with familial polyposis, a sarcomatous tumour has not been previously described. In the clinical assessment of patients with familial polyposis the possibility should be considered of associated tumours in extracolonic sites, including the central nervous system.
结肠家族性息肉病与身体其他部位良性和恶性、软和硬结缔组织肿瘤的发病率增加有关。本文报告了一名35岁患有家族性息肉病的男性患者的临床细节和尸检结果，该患者死于累及脑干和上脊髓的网状细胞肉瘤（微胶质瘤）。虽然此前已有报道其他中枢神经系统恶性肿瘤与家族性息肉病有关，但肉瘤样肿瘤此前尚未见描述。在对家族性息肉病患者进行临床评估时，应考虑到结肠外部位包括中枢神经系统发生相关肿瘤的可能性。
