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海德尔综合征:严重主动脉瓣狭窄和胃肠道出血的挑战性病例。

Heyde's syndrome: a challenging case of severe aortic stenosis and gastrointestinal bleeding.

机构信息

Department of Medicine, Baptist Hospitals of Southeast Texas, Beaumont, Texas, USA.

Department of Hematology and Oncology, Mayo Clinic, Jacksonville, Florida, USA

出版信息

BMJ Case Rep. 2024 Apr 17;17(4):e258316. doi: 10.1136/bcr-2023-258316.

Abstract

We present the case of an elderly man with a history of diastolic congestive heart failure, severe aortic stenosis and atrial fibrillation, who presented with fatigue, weakness, coffee ground emesis and black tarry stool. Haemoglobin was 68 g/L. Lactate dehydrogenase was elevated at 1038. Evaluation by cardiology and gastroenterology specialists revealed reflux oesophagitis and a mild hiatal hernia on oesophagogastroduodenoscopy, normal colonoscopy and small bowel series without obstruction. Capsule endoscopy identified angiodysplasia in the small intestine.The patient was diagnosed with Heyde's syndrome based on the triad of severe aortic stenosis, gastrointestinal bleeding from angiodysplasia and acquired von Willebrand syndrome. The patient underwent transcatheter aortic valve replacement, resulting in the resolution of symptoms.Heyde's syndrome represents a challenging clinical entity requiring a multidisciplinary approach for accurate diagnosis and management. Early recognition, prompt intervention and interdisciplinary collaboration are crucial in optimising patient outcomes.

摘要

我们报告了一例老年男性病例,该患者有舒张性充血性心力衰竭、严重主动脉瓣狭窄和心房颤动病史,表现为疲劳、虚弱、咖啡渣样呕吐和黑柏油样便。血红蛋白为 68g/L。乳酸脱氢酶升高至 1038。心脏病学和胃肠病学专家的评估显示,食管胃十二指肠镜检查发现反流性食管炎和轻度食管裂孔疝,结肠镜检查和小肠系列检查正常无梗阻。胶囊内镜发现小肠的血管发育不良。该患者基于严重主动脉瓣狭窄、血管发育不良引起的胃肠道出血和获得性血管性血友病综合征,被诊断为 Heyde 综合征。患者接受了经导管主动脉瓣置换术,症状得到缓解。Heyde 综合征是一种具有挑战性的临床实体,需要多学科方法进行准确诊断和管理。早期识别、及时干预和跨学科合作对于优化患者的预后至关重要。

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本文引用的文献

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