Waldron Christina, Ito Satoko, Wang Daniel, Allen Cecily, Viswanathan Giri, Bona Robert D, Cuker Adam, Goshua George
Yale School of Medicine, New Haven, CT.
Section of Hematology, Department of Internal Medicine, Yale School of Medicine, New Haven, CT.
Blood. 2024 May 30;143(22):2332-2335. doi: 10.1182/blood.2024024209.
We evaluated the cost-effectiveness of prophylaxis with recombinant von Willebrand factor (rVWF) vs with plasma-derived von Willebrand factor (pdVWF) for patients with severe Von Willebrand disease. We found that rVWF is a cost-saving factor replacement compared with pdVWF across all willingness-to-pay thresholds in the United States.
我们评估了重组血管性血友病因子(rVWF)与血浆源性血管性血友病因子(pdVWF)对重度血管性血友病患者进行预防治疗的成本效益。我们发现,在美国所有支付意愿阈值下,与pdVWF相比,rVWF是一种节省成本的因子替代物。