Duke University School of Medicine, Duke University Medical Center, Durham, NC, USA.
Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC, USA.
BMC Musculoskelet Disord. 2024 Apr 20;25(1):304. doi: 10.1186/s12891-024-07418-w.
Clinicians and public health professionals have allocated resources to curb opioid over-prescription and address psychological needs among patients with musculoskeletal pain. However, associations between psychological distress, risk of surgery, and opioid prescribing among those with hip pathologies remain unclear.
Using a retrospective cohort study design, we identified patients that were evaluated for hip pain from January 13, 2020 to October 27, 2021. Patients' surgical histories and postoperative opioid prescriptions were extracted via chart review. Risk of hip surgery within one year of evaluation was analyzed using multivariable logistic regression. Multivariable linear regression was employed to predict average morphine milligram equivalents (MME) per day of opioid prescriptions within the first 30 days after surgery. Candidate predictors included age, gender, race, ethnicity, employment, insurance type, hip function and quality of life on the International Hip Outcome Tool (iHOT-12), and psychological distress phenotype using the OSPRO Yellow Flag (OSPRO-YF) Assessment Tool.
Of the 672 patients, n = 350 (52.1%) underwent orthopaedic surgery for hip pain. In multivariable analysis, younger patients, those with TRICARE/other government insurance, and those with a high psychological distress phenotype had higher odds of surgery. After adding iHOT-12 scores, younger patients and lower iHOT-12 scores were associated with higher odds of surgery, while Black/African American patients had lower odds of surgery. In multivariable analysis of average MME, patients with periacetabular osteotomy (PAO) received opioid prescriptions with significantly higher average MME than those with other procedures, and surgery type was the only significant predictor. Post-hoc analysis excluding PAO found higher average MME for patients undergoing hip arthroscopy (compared to arthroplasty or other non-PAO procedures) and significantly lower average MME for patients with public insurance (Medicare/Medicaid) compared to those with private insurance. Among those only undergoing arthroscopy, older age and having public insurance were associated with opioid prescriptions with lower average MME. Neither iHOT-12 scores nor OSPRO-YF phenotype assignment were significant predictors of postoperative mean MME.
Psychological distress characteristics are modifiable targets for rehabilitation programs, but their use as prognostic factors for risk of orthopaedic surgery and opioid prescribing in patients with hip pain appears limited when considered alongside other commonly collected clinical information such as age, insurance, type of surgery pursued, and iHOT-12 scores.
临床医生和公共卫生专业人员已经分配资源来遏制阿片类药物的过度处方,并解决肌肉骨骼疼痛患者的心理需求。然而,髋部病变患者的心理困扰、手术风险和阿片类药物处方之间的关联仍不清楚。
使用回顾性队列研究设计,我们确定了 2020 年 1 月 13 日至 2021 年 10 月 27 日期间因髋部疼痛接受评估的患者。通过图表审查提取患者的手术史和术后阿片类药物处方。使用多变量逻辑回归分析一年内评估后髋关节手术的风险。使用多变量线性回归预测术后 30 天内阿片类药物处方的平均吗啡毫克当量(MME)。候选预测因子包括年龄、性别、种族、民族、就业、保险类型、髋关节功能和国际髋关节结果工具(iHOT-12)的生活质量,以及使用 OSPRO 黄色标志(OSPRO-YF)评估工具的心理困扰表型。
在 672 名患者中,n=350(52.1%)因髋部疼痛接受矫形手术。多变量分析显示,年轻患者、接受 TRICARE/其他政府保险的患者和心理困扰表型较高的患者手术的可能性更高。加入 iHOT-12 评分后,年轻患者和较低的 iHOT-12 评分与更高的手术可能性相关,而黑人和非裔美国人患者的手术可能性较低。在平均 MME 的多变量分析中,接受髋臼周围截骨术(PAO)的患者接受阿片类药物处方的平均 MME 明显高于接受其他手术的患者,手术类型是唯一显著的预测因子。排除 PAO 的事后分析发现,接受髋关节镜检查(与关节置换或其他非 PAO 手术相比)的患者的平均 MME 更高,而接受公共保险(医疗保险/医疗补助)的患者的平均 MME 明显低于接受私人保险的患者。在仅接受关节镜检查的患者中,年龄较大和有公共保险与较低的平均 MME 阿片类药物处方相关。iHOT-12 评分和 OSPRO-YF 表型分配均不是术后平均 MME 的显著预测因子。
心理困扰特征是康复计划的可改变目标,但当考虑到其他常见收集的临床信息(如年龄、保险、所进行的手术类型和 iHOT-12 评分)时,它们作为髋部疼痛患者手术风险和阿片类药物处方的预后因素的作用似乎有限。