Younis Omar, Odeh Anas, Saifi Motaz, Dumaidi Yazan, Kazlak Mazen
Department of Medicine, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.
Department of Otorhinolaryngology, An-Najah National University Hospital, Nablus, Palestine.
Radiol Case Rep. 2024 Apr 13;19(7):2603-2607. doi: 10.1016/j.radcr.2024.03.050. eCollection 2024 Jul.
Extramedullary plasmacytoma (EMP) is an uncommon tumor marked by the monoclonal growth of plasma cells without the characteristics of multiple myeloma. EMP represents 3% of all plasma cell tumors. An 89-year-old male patient with hypertension was admitted to our tertiary care hospital with uncontrolled unilateral epistaxis. After a year and a half of recurring epistaxis, the patient's bleeding became more frequent and could no longer be controlled with nasal packing. Angiofibroma was suspected as the initial differential diagnosis, and angiofibroma embolization was performed. The patient experienced difficulty swallowing and slurred speech and was diagnosed with an ischemic stroke. However, antiplatelet and tranexamic acid medications were contraindicated due to bleeding risks. The patient underwent functional endoscopic sinus surgery, and unexpectedly, histology results revealed a plasmacytoma. After surgery, the patient remained stable and was discharged for further management.
髓外浆细胞瘤（EMP）是一种罕见的肿瘤，其特征为浆细胞单克隆生长，且不具备多发性骨髓瘤的特点。EMP占所有浆细胞肿瘤的3%。一名89岁的男性高血压患者因单侧鼻出血控制不佳入住我们的三级护理医院。在反复鼻出血一年半后，患者出血变得更加频繁，鼻腔填塞已无法控制出血。最初怀疑为血管纤维瘤并进行了血管纤维瘤栓塞术。患者出现吞咽困难和言语不清，被诊断为缺血性中风。然而，由于出血风险，抗血小板药物和氨甲环酸药物均为禁忌。患者接受了功能性鼻内镜鼻窦手术，出乎意料的是，组织学结果显示为浆细胞瘤。术后患者情况稳定，出院以便进一步治疗。
