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COVID-19 合并糖尿病并发口腔毛霉病:病例报告及文献复习。

Oral mucormycosis associated with COVID-19 and diabetes mellitus: Case report and literature review.

机构信息

Departamento de Investigación, Hospital Regional de la Orinoquía, Yopal, Colombia.

Cirugía Maxilofacial, Hospital Regional de la Orinoquía, Yopal, Colombia.

出版信息

Biomedica. 2024 Mar 31;44(1):10-15. doi: 10.7705/biomedica.6970.

Abstract

Mucormycosis is an invasive opportunistic fungal infection with high mortality, mainly detected in people with COVID-19, especially those with underlying diseases such as diabetes mellitus. Mucormycosis prevalence is 0.005 to 1.7 cases per million inhabitants, and it has been increasing in countries like India and Pakistan. This mycosis can affect different organs, and clinical manifestations reflect the transmission mechanism. Frequent forms are rhino-orbital-cerebral and pulmonary. This disease should be suspected in patients with necrotic injuries on mucous membranes or skin. We present a case of a patient with diabetes mellitus and diagnosed with oral mucormycosis associated with COVID-19.

摘要

毛霉病是一种侵袭性机会性真菌感染,死亡率高,主要发生在 COVID-19 患者中,特别是患有糖尿病等基础疾病的患者。毛霉病的患病率为每百万居民中有 0.005 至 1.7 例,在印度和巴基斯坦等国家呈上升趋势。这种真菌感染可影响不同的器官,临床表现反映了传播机制。常见的形式是鼻-眶-脑和肺。对于有粘膜或皮肤坏死性损伤的患者,应怀疑本病。我们报告了一例糖尿病患者,诊断为 COVID-19 相关的口腔毛霉病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c9d/11186624/f2645e7e5acf/2590-7379-bio-44-01-6970-gf1.jpg

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