Department of Neurology, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, P. R. China.
BMC Neurol. 2024 Apr 25;24(1):137. doi: 10.1186/s12883-024-03645-9.
Scrub typhus is an acute infectious disease caused by Orientia tsutsugamushi. Guillain-Barre syndrome (GBS) is an autoimmune-mediated peripheral neuropathy with a frequent history of prodromal infections, but GBS associated with scrub typhus is very rare.
We report a 51-year-old male patient who developed dysarthria and peripheral facial paralysis following the cure of scfrub typhus. CSF examination and electrophysiological findings suggested a diagnosis of GBS. After treatment with intravenous immunoglobulin, the patient's neurological condition improved rapidly.
Scrub typhus infection is likely to be a potential predisposing factor in GBS, while scrub typhus-associated GBS has a favorable prognosis.
恙虫病是由恙虫东方体引起的急性传染病。吉兰-巴雷综合征(GBS)是一种自身免疫介导的周围神经病,常伴有前驱感染史,但与恙虫病相关的 GBS 非常罕见。
我们报告了一例 51 岁男性患者,在恙虫病治愈后出现构音障碍和周围性面瘫。CSF 检查和电生理检查结果提示 GBS 诊断。患者接受静脉注射免疫球蛋白治疗后,神经功能迅速改善。
恙虫病感染可能是 GBS 的潜在诱发因素,而恙虫病相关的 GBS 预后良好。