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恙虫病后格林-巴利综合征:病例报告及文献复习。

Guillain-Barre syndrome following scrub typhus: a case report and literature review.

机构信息

Department of Neurology, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, P. R. China.

出版信息

BMC Neurol. 2024 Apr 25;24(1):137. doi: 10.1186/s12883-024-03645-9.

Abstract

BACKGROUND

Scrub typhus is an acute infectious disease caused by Orientia tsutsugamushi. Guillain-Barre syndrome (GBS) is an autoimmune-mediated peripheral neuropathy with a frequent history of prodromal infections, but GBS associated with scrub typhus is very rare.

CASE PRESENTATION

We report a 51-year-old male patient who developed dysarthria and peripheral facial paralysis following the cure of scfrub typhus. CSF examination and electrophysiological findings suggested a diagnosis of GBS. After treatment with intravenous immunoglobulin, the patient's neurological condition improved rapidly.

CONCLUSIONS

Scrub typhus infection is likely to be a potential predisposing factor in GBS, while scrub typhus-associated GBS has a favorable prognosis.

摘要

背景

恙虫病是由恙虫东方体引起的急性传染病。吉兰-巴雷综合征(GBS)是一种自身免疫介导的周围神经病,常伴有前驱感染史,但与恙虫病相关的 GBS 非常罕见。

病例介绍

我们报告了一例 51 岁男性患者,在恙虫病治愈后出现构音障碍和周围性面瘫。CSF 检查和电生理检查结果提示 GBS 诊断。患者接受静脉注射免疫球蛋白治疗后,神经功能迅速改善。

结论

恙虫病感染可能是 GBS 的潜在诱发因素,而恙虫病相关的 GBS 预后良好。

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本文引用的文献

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