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脊髓损伤成年人的肌肉骨骼发病率:一项全国性队列研究。

Musculoskeletal morbidity in adults with spinal cord injuries: A nationwide cohort study.

机构信息

Department of Neurosurgery, Pohang Naval Hospital, Pohang, Korea.

Department of Precision Medicine, Sungkyunkwan University School of Medicine, Suwon, Korea.

出版信息

NeuroRehabilitation. 2024;54(4):599-610. doi: 10.3233/NRE-230263.

DOI:10.3233/NRE-230263
PMID:38669487
Abstract

BACKGROUND

An increase in the demand for quality of life following spinal cord injuries (SCIs) is associated with an increase in musculoskeletal (MSK) pain, highlighting the need for preventive measure research.

OBJECTIVE

This study aimed to evaluate the incidence and hazards of MSK morbidities among Korean adults with SCIs, as well as the influence of SCI location on MSK morbidities.

METHODS

Patient populations were selected from Korean National Health Insurance Service data (n = 276). The control group included individuals without SCIs (n = 10,000). We compared the incidences and determined the unadjusted and adjusted hazard ratios (HRs) of common MSK morbidities (osteoarthritis, connective tissue disorders, sarcopenia, myalgia, neuralgia, rheumatoid arthritis, myositis, and musculoskeletal infections) based on the location of injury (cervical, thoracic, or lumbar).

RESULTS

Adults with SCIs had a higher incidence of MSK morbidity (48.45% vs. 36.6%) and a lower survival probability than those without SCIs. The incidence of MSK morbidity and survival probabilities were not significantly different for cervical cord injuries, whereas both measures were significantly different for thoracic and lumbar injuries.

CONCLUSION

SCI increases the risk of MSK morbidity. Lumbar SCI is associated with a higher incidence and risk of MSK morbidity than are cervical or thoracic SCIs.

摘要

背景

脊髓损伤(SCI)后对生活质量的需求增加与肌肉骨骼(MSK)疼痛的增加有关,这凸显了对预防措施研究的需求。

目的

本研究旨在评估韩国 SCI 成年人的 MSK 发病率和发病率,并探讨 SCI 部位对 MSK 发病率的影响。

方法

从韩国国家健康保险服务数据中选择患者人群(n=276)。对照组包括无 SCI 个体(n=10,000)。我们比较了发病率,并根据损伤部位(颈椎、胸椎或腰椎)确定了常见 MSK 疾病(骨关节炎、结缔组织疾病、肌肉减少症、肌痛、神经痛、类风湿关节炎、肌炎和肌肉骨骼感染)的未调整和调整后的危险比(HRs)。

结果

与无 SCI 个体相比,SCI 成年人的 MSK 发病率(48.45%对 36.6%)更高,生存概率更低。颈椎损伤的 MSK 发病率和生存概率无显著差异,而胸椎和腰椎损伤的这两个指标均有显著差异。

结论

SCI 会增加 MSK 发病率的风险。与颈椎或胸椎 SCI 相比,腰椎 SCI 与更高的 MSK 发病率和风险相关。

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