Suppr超能文献

经乙状窦前迷路后入路选择性前庭神经切断术治疗梅尼埃病

Selective Vestibular Neurectomy through the Presigmoid Retrolabyrinthine Approach in the Treatment of Meniere's Disease.

作者信息

Salvinelli Fabrizio, Bonifacio Francesca, Capece Mara, Aiudi Denis, Iacoangeli Alessio, Greco Fabio, Gladi Maurizio, Iacoangeli Maurizio

机构信息

UOC di Otorinolaringoiatria, Fondazione Policlinico Universitario Campus Bio-Medico, 60126 Rome, Italy.

Clinica Universitaria di Neurochirurgia, Università Politecnica delle Marche, Azienda Ospedaliero Universitaria delle Marche, 60126 Ancona, Italy.

出版信息

Brain Sci. 2024 Apr 11;14(4):369. doi: 10.3390/brainsci14040369.

Abstract

BACKGROUND

Meniere's disease (MD) is a disabling disease, especially in patients who are refractory to medical therapy. Moreover, selective vestibular neurectomy (VN), in these selected cases, can be considered a surgical alternative which preserves hearing function and facial nerve.

METHODS

We retrospectively studied 23 patients with MD diagnosis and history of failed extradural endolymphatic sac surgery (ELSS) who underwent combined micro-endoscopic selective VN, between January 2019 and August 2023, via a presigmoid retrolabyrinthine approach. All patients were stratified according to clinical features, assessing preoperative and postoperative hearing levels and quality of life.

RESULTS

At the maximum present follow-up of 2 years, this procedure is characterized by a low rate of complications and about 90% vertigo control after surgery. No definitive facial palsy or hearing loss was described in this series. One patient required reintervention for a CSF fistula. Statistically significant ( = 0.001) difference was found between the preoperative and the postoperative performance in terms of physical, functional, and emotive scales assessed via the DHI questionnaire.

CONCLUSIONS

Selective VN via a presigmoid retrolabyrinthine approach is a safe procedure for intractable vertigo associated with MD, when residual hearing function still exists. The use of the endoscope and intraoperative neuromonitoring guaranteed a precise result, saving the cochlear fibers and facial nerve. The approach for VN is a familiar procedure to the otolaryngologist, as is lateral skull base anatomy to the neurosurgeon; therefore, the best results are obtained with multidisciplinary teamwork.

摘要

背景

梅尼埃病(MD)是一种致残性疾病,尤其是对于药物治疗无效的患者。此外,在这些特定病例中,选择性前庭神经切除术(VN)可被视为一种保留听力功能和面神经的手术替代方案。

方法

我们回顾性研究了2019年1月至2023年8月期间通过乙状窦前迷路后入路接受联合微内镜选择性VN的23例诊断为MD且硬膜外内淋巴囊手术(ELSS)失败的患者。所有患者根据临床特征进行分层,评估术前和术后的听力水平及生活质量。

结果

在目前最长2年的随访中,该手术并发症发生率低,术后眩晕控制率约为90%。本系列中未描述明确的面神经麻痹或听力损失。1例患者因脑脊液漏需要再次干预。通过DHI问卷评估的身体、功能和情感量表方面,术前和术后表现存在统计学显著差异(P = 0.001)。

结论

当仍存在残余听力功能时,通过乙状窦前迷路后入路进行选择性VN是治疗与MD相关的顽固性眩晕的安全手术。内镜的使用和术中神经监测保证了精确的结果,保留了耳蜗纤维和面神经。VN手术对耳鼻喉科医生来说是一种熟悉的手术,对神经外科医生来说侧颅底解剖也是如此;因此,多学科团队合作能取得最佳效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99fd/11048401/c02ce17a0360/brainsci-14-00369-g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验