Salvinelli Fabrizio, Bonifacio Francesca, Capece Mara, Aiudi Denis, Iacoangeli Alessio, Greco Fabio, Gladi Maurizio, Iacoangeli Maurizio
UOC di Otorinolaringoiatria, Fondazione Policlinico Universitario Campus Bio-Medico, 60126 Rome, Italy.
Clinica Universitaria di Neurochirurgia, Università Politecnica delle Marche, Azienda Ospedaliero Universitaria delle Marche, 60126 Ancona, Italy.
Brain Sci. 2024 Apr 11;14(4):369. doi: 10.3390/brainsci14040369.
Meniere's disease (MD) is a disabling disease, especially in patients who are refractory to medical therapy. Moreover, selective vestibular neurectomy (VN), in these selected cases, can be considered a surgical alternative which preserves hearing function and facial nerve.
We retrospectively studied 23 patients with MD diagnosis and history of failed extradural endolymphatic sac surgery (ELSS) who underwent combined micro-endoscopic selective VN, between January 2019 and August 2023, via a presigmoid retrolabyrinthine approach. All patients were stratified according to clinical features, assessing preoperative and postoperative hearing levels and quality of life.
At the maximum present follow-up of 2 years, this procedure is characterized by a low rate of complications and about 90% vertigo control after surgery. No definitive facial palsy or hearing loss was described in this series. One patient required reintervention for a CSF fistula. Statistically significant ( = 0.001) difference was found between the preoperative and the postoperative performance in terms of physical, functional, and emotive scales assessed via the DHI questionnaire.
Selective VN via a presigmoid retrolabyrinthine approach is a safe procedure for intractable vertigo associated with MD, when residual hearing function still exists. The use of the endoscope and intraoperative neuromonitoring guaranteed a precise result, saving the cochlear fibers and facial nerve. The approach for VN is a familiar procedure to the otolaryngologist, as is lateral skull base anatomy to the neurosurgeon; therefore, the best results are obtained with multidisciplinary teamwork.
梅尼埃病(MD)是一种致残性疾病,尤其是对于药物治疗无效的患者。此外,在这些特定病例中,选择性前庭神经切除术(VN)可被视为一种保留听力功能和面神经的手术替代方案。
我们回顾性研究了2019年1月至2023年8月期间通过乙状窦前迷路后入路接受联合微内镜选择性VN的23例诊断为MD且硬膜外内淋巴囊手术(ELSS)失败的患者。所有患者根据临床特征进行分层,评估术前和术后的听力水平及生活质量。
在目前最长2年的随访中,该手术并发症发生率低,术后眩晕控制率约为90%。本系列中未描述明确的面神经麻痹或听力损失。1例患者因脑脊液漏需要再次干预。通过DHI问卷评估的身体、功能和情感量表方面,术前和术后表现存在统计学显著差异(P = 0.001)。
当仍存在残余听力功能时,通过乙状窦前迷路后入路进行选择性VN是治疗与MD相关的顽固性眩晕的安全手术。内镜的使用和术中神经监测保证了精确的结果,保留了耳蜗纤维和面神经。VN手术对耳鼻喉科医生来说是一种熟悉的手术,对神经外科医生来说侧颅底解剖也是如此;因此,多学科团队合作能取得最佳效果。