Jo Youn Yi, Kim Seong Min, Park Chun Gon, Kim Ji Woong, Kwak Hyun Jeong
Department of Anesthesiology and Pain Medicine, College of Medicine, Gil Hospital, Gachon University, Incheon 21565, Republic of Korea.
Department of Surgery, College of Medicine, Gil Hospital, Gachon University, Incheon 21565, Republic of Korea.
J Pers Med. 2024 Apr 11;14(4):405. doi: 10.3390/jpm14040405.
Obesity negatively affects hemodynamics and cerebral physiology. We investigated the effect of the utilization of an intermittent pneumatic compression (IPC) device on hemodynamics and cerebral physiology in patients undergoing laparoscopic bariatric surgery under general anesthesia with lung-protective ventilation. Sixty-four patients (body mass index > 30 kg/m) were randomly assigned to groups that received an IPC device (IPC group, = 32) and did not (control group, = 32). The mean arterial pressure (MAP), heart rate (HR), need for vasopressors, cerebral oxygen saturation (rSO), and cerebral desaturation events were recorded. The incidence of intraoperative hypotension was not significantly different between groups ( = 0.153). Changes in MAP and HR over time were similar between groups ( = 0.196 and = 0.705, respectively). The incidence of intraoperative cerebral desaturation was not significantly different between groups ( = 0.488). Changes in rSO over time were similar between the two groups ( = 0.190) during pneumoperitoneum. Applying IPC to patients with obesity in the steep reverse Trendelenburg position may not improve hemodynamic parameters, vasopressor requirements, or rSO values during pneumoperitoneum under lung-protective ventilation. During laparoscopic bariatric surgery, IPC alone has limitations in improving hemodynamics and cerebral physiology.
肥胖对血流动力学和脑生理学有负面影响。我们研究了在全身麻醉下采用肺保护性通气进行腹腔镜减肥手术的患者中,使用间歇性充气加压(IPC)装置对血流动力学和脑生理学的影响。64例患者(体重指数>30kg/m²)被随机分为接受IPC装置的组(IPC组,n = 32)和未接受的组(对照组,n = 32)。记录平均动脉压(MAP)、心率(HR)、血管升压药的使用需求、脑氧饱和度(rSO₂)和脑去饱和事件。两组术中低血压的发生率无显著差异(P = 0.153)。两组间MAP和HR随时间的变化相似(分别为P = 0.196和P = 0.705)。两组术中脑去饱和的发生率无显著差异(P = 0.488)。在气腹期间,两组间rSO₂随时间的变化相似(P = 0.190)。在肺保护性通气下对处于陡峭反向头低脚高位的肥胖患者应用IPC,可能无法改善气腹期间的血流动力学参数、血管升压药需求或rSO₂值。在腹腔镜减肥手术期间,单独使用IPC在改善血流动力学和脑生理学方面存在局限性。