Schlatzer Christian, Berg Jan, Duru Firat, Brunckhorst Corinna, Saguner Ardan M, Haegeli Laurent M
University Hospital of Zurich, 8091 Zurich, Switzerland.
Department of Cardiology, Medical University Department, Kantonsspital Aarau Tellstrasse 25, 5001 Aarau, Switzerland.
J Clin Med. 2024 Apr 17;13(8):2310. doi: 10.3390/jcm13082310.
: Catheter ablation in patients with ventricular arrhythmias (VA), such as ventricular tachycardias (VT) or frequent premature ventricular complexes (PVC), is increasingly considered an effective and safe therapy when performed in experienced centers. This study sought to determine acute success rates and complication rates of ablation procedures for patients with VA in a Swiss tertiary care center. All patients who underwent ablation therapy for VT and PVC at the University Heart Center in Zurich, Switzerland, between March 2012 and April 2017 were included in this analysis. A total of 120 patients underwent catheter ablation for VT and PVC (69 and 51, respectively). Seventy percent of patients were male, and the mean age was 55.3 years. The most common indication for ablation was high PVC burden (47.5%), followed by paroxysmal VT (38.3%), ICD shocks (23.3%), incessant VT (12.5%), electrical storm (7.5%), and syncope (3.3%). Acute success rates for VT and PVC ablations were 94.2% and 92.2%, respectively. Rates for complications (including major and minor) for VT and PVC were 10.1% and 7.8%, respectively. Complications occurred only in patients with structural heart disease; no complications were noted in structurally normal hearts. Our results suggest that catheter ablation for VT and PVC has high acute success rates with a reasonable risk for complications in the setting of tertiary care centers, comparable to those reported in other studies.
对于患有室性心律失常(VA)的患者,如室性心动过速(VT)或频发室性早搏(PVC),在经验丰富的中心进行导管消融越来越被认为是一种有效且安全的治疗方法。本研究旨在确定瑞士一家三级医疗中心VA患者消融手术的急性成功率和并发症发生率。纳入了2012年3月至2017年4月期间在瑞士苏黎世大学心脏中心接受VT和PVC消融治疗的所有患者。共有120例患者接受了VT和PVC导管消融(分别为69例和51例)。70%的患者为男性,平均年龄为55.3岁。最常见的消融指征是高PVC负荷(47.5%),其次是阵发性VT(38.3%)、植入式心律转复除颤器(ICD)电击(23.3%)、持续性VT(12.5%)、电风暴(7.5%)和晕厥(3.3%)。VT和PVC消融的急性成功率分别为94.2%和92.2%。VT和PVC的并发症发生率(包括主要和次要并发症)分别为10.1%和7.8%。并发症仅发生在有结构性心脏病的患者中;结构正常的心脏未发现并发症。我们的结果表明,在三级医疗中心环境下,VT和PVC的导管消融具有较高的急性成功率,并发症风险合理,与其他研究报道的结果相当。