Brauckmann Vesta, Block Ole Moritz, Pardo Luis A, Lehmann Wolfgang, Braatz Frank, Felmerer Gunther, Mönnighoff Sebastian, Ernst Jennifer
Department of Trauma Surgery, Hannover Medical School, Carl-Neuberg-Straße 1, 30625 Hannover, Germany.
Department of Trauma Surgery, Orthopedic Surgery and Plastic Surgery, University Medical Center, 37075 Göttingen, Germany.
Medicina (Kaunas). 2024 Mar 30;60(4):565. doi: 10.3390/medicina60040565.
Medical registries evolved from a basic epidemiological data set to further applications allowing deriving decision making. Revision rates after non-traumatic amputation are high and dramatically impact the following rehabilitation of the amputee. Risk scores for revision surgery after non-traumatic lower limb amputation are still missing. The main objective was to create an amputation registry allowing us to determine risk factors for revision surgery after non-traumatic lower-limb amputation and to develop a score for an early detection and decision-making tool for the therapeutic course of patients at risk for non-traumatic lower limb amputation and/or revision surgery. : Retrospective data analysis was of patients with major amputations lower limbs in a four-year interval at a University Hospital of maximum care. Medical records of 164 patients analysed demographics, comorbidities, and amputation-related factors. Descriptive statistics analysed demographics, prevalence of amputation level and comorbidities of non-traumatic lower limb amputees with and without revision surgery. Correlation analysis identified parameters determining revision surgery. In 4 years, 199 major amputations were performed; 88% were amputated for non-traumatic reasons. A total of 27% of the non-traumatic cohort needed revision surgery. Peripheral vascular disease (PVD) (72%), atherosclerosis (69%), diabetes (42%), arterial hypertension (38%), overweight (BMI > 25), initial gangrene (47%), sepsis (19%), age > 68.2 years and nicotine abuse (17%) were set as relevant within this study and given a non-traumatic amputation score. Correlation analysis revealed delayed wound healing (confidence interval: 64.1% (47.18%; 78.8%)), a hospital length of stay before amputation of longer than 32 days (confidence interval: 32.3 (23.2; 41.3)), and a BKA amputation level (confidence interval: 74.4% (58%; 87%)) as risk factors for revision surgery after non-traumatic amputation. A combined score including all parameters was drafted to identify non-traumatic amputees at risk for revision surgery. : Our results describe novel scoring systems for risk assessment for non-traumatic amputations and for revision surgery at non-traumatic amputations. It may be used after further prospective evaluation as an early-warning system for amputated limbs at risk of revision.
医学登记系统从基本的流行病学数据集发展到可用于进一步的应用,从而辅助决策制定。非创伤性截肢后的翻修率很高,对截肢者随后的康复产生重大影响。目前仍缺乏非创伤性下肢截肢后翻修手术的风险评分。主要目标是创建一个截肢登记系统,使我们能够确定非创伤性下肢截肢后翻修手术的风险因素,并为有非创伤性下肢截肢和/或翻修手术风险的患者的治疗过程开发一个早期检测和决策工具。:对一家大学医院重症监护病房四年间接受下肢大截肢手术的患者进行回顾性数据分析。分析了164例患者的病历,包括人口统计学、合并症和与截肢相关的因素。描述性统计分析了非创伤性下肢截肢患者(有或无翻修手术)的人口统计学、截肢水平患病率和合并症。相关性分析确定了决定翻修手术的参数。在4年中,共进行了199例大截肢手术;88%是因非创伤性原因截肢。非创伤性队列中共有27%的患者需要翻修手术。外周血管疾病(PVD)(72%)、动脉粥样硬化(69%)、糖尿病(42%)、动脉高血压(38%)、超重(BMI>25)、初始坏疽(47%)、败血症(19%)、年龄>68.2岁和尼古丁滥用(17%)在本研究中被视为相关因素,并给出了非创伤性截肢评分。相关性分析显示,伤口愈合延迟(置信区间:64.1%(47.18%;78.8%))、截肢前住院时间超过32天(置信区间:32.3(23.2;41.3))和膝下截肢水平(置信区间:74.4%(58%;87%))是非创伤性截肢后翻修手术的风险因素。起草了一个包含所有参数的综合评分,以识别有翻修手术风险的非创伤性截肢患者。:我们的结果描述了非创伤性截肢风险评估和非创伤性截肢翻修手术的新评分系统。经过进一步的前瞻性评估后,它可作为有翻修风险的截肢肢体的早期预警系统使用。