1例社区获得性杀白细胞素阳性耐甲氧西林金黄色葡萄球菌（MRSA）坏死性肺炎患者经两种抗MRSA药物成功治愈。
A case of community-acquired Panton-Valentine leukocidin-positive methicillin-resistant (MRSA) necrotizing pneumonia successfully treated with two anti-MRSA drugs.
作者信息
Shiiba Ritsuya, Sano Masahiro, Kogure Yoshihito, Murao Hiroto, Takigawa Yuki, Torii Atsushi, Yamada Arisa, Shinohara Yuka, Niwa Hideyuki, Kitagawa Chiyoe, Oki Masahide
机构信息
Department of Respiratory Medicine, NHO Nagoya Medical Center, Nagoya, Japan.
出版信息
Respir Med Case Rep. 2024 Apr 18;49:102023. doi: 10.1016/j.rmcr.2024.102023. eCollection 2024.
Abstract
A 22-year-old Vietnamese man was referred to our hospital owing to cough, dyspnea, and difficulty moving. The patient was diagnosed with community-acquired Panton-Valentine leukocidin-positive methicillin-resistant (MRSA) bacteremia and necrotizing pneumonia. Treatment involved vancomycin (VCM) and meropenem, and the MRSA bacteremia improved. However, lung tissue destruction progressed. Therefore, linezolid was added to the VCM regimen, and this intervention led to the patient's recovery, and he was discharged from the hospital. Here, we report a case in which the patient was treated with a combination of two anti-MRSA drugs and was cured.
摘要
一名22岁的越南男子因咳嗽、呼吸困难和行动困难被转诊至我院。该患者被诊断为社区获得性杀白细胞素阳性耐甲氧西林金黄色葡萄球菌（MRSA）菌血症和坏死性肺炎。治疗采用了万古霉素（VCM）和美罗培南，MRSA菌血症有所改善。然而，肺组织破坏仍在进展。因此，在VCM治疗方案中加入了利奈唑胺，这一干预措施使患者康复，并出院。在此，我们报告一例患者接受两种抗MRSA药物联合治疗并治愈的病例。
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