Chaudhari Pranav, Sawant Rucha, Bordoloi Meghna, Kumar Sunil, Acharya Sourya
Medicine, Jawaharlal Nehru Medical College, Wardha, IND.
Cureus. 2024 Mar 27;16(3):e57036. doi: 10.7759/cureus.57036. eCollection 2024 Mar.
The uncommon but dangerous condition known as emphysematous pyelonephritis (EPN) usually affects people with diabetes. This potentially fatal illness is characterized by gas-forming necrosis of the kidneys and surrounding tissues, typically brought on by urinary tract bacteria. Fungal EPN, less prevalent than bacterial EPN, has been reported in a few isolated cases. Cultures of the urine or blood often detect the infection. With an 18% fatality rate, EPN is still a serious illness despite advancements in therapy. High suspicion for EPN is critical in diabetic patients experiencing pyelonephritis. Interestingly, women with uncontrolled diabetes seem to be more susceptible. While is the usual culprit, rare cases involve species. This case report describes a pathogen that is rarely encountered and causes EPN. A diabetic woman in her sixties without prior hospitalizations presented with a sudden fever and excruciating abdominal pain. The patient also complained of abdominal distension with reduced urine output and breathlessness at rest. Investigations revealed left-sided EPN that was "WAN Type 1." We treated the patient according to culture sensitivity with systemic antifungals, percutaneous nephrostomy (PCN), and ureteral stenting (double J stent or DJ stent). Following successful treatment, the patient recovered and was discharged. This case highlights the importance of considering uncommon causes, even in seemingly typical presentations of EPN. Our case is unique as the patient had an infection with non-albicans Candida with a complication of anuric acute kidney injury and uncontrolled diabetes mellitus.
一种罕见但危险的病症,即气肿性肾盂肾炎(EPN),通常影响糖尿病患者。这种潜在致命疾病的特征是肾脏及周围组织的产气性坏死,通常由尿路细菌引起。真菌性EPN比细菌性EPN少见,已有少数孤立病例的报道。尿液或血液培养常可检测到感染。尽管治疗有进展,但EPN的死亡率仍为18%,仍是一种严重疾病。对患有肾盂肾炎的糖尿病患者高度怀疑EPN至关重要。有趣的是,糖尿病控制不佳的女性似乎更易患病。虽然 是常见病因,但罕见病例涉及 菌种。本病例报告描述了一种罕见的导致EPN的病原体。一名60多岁未曾住院的糖尿病女性突然发热并伴有剧烈腹痛。患者还主诉腹胀、尿量减少及静息时呼吸困难。检查发现左侧EPN为“WAN 1型”。我们根据培养药敏结果对患者进行了全身抗真菌治疗、经皮肾造瘘术(PCN)和输尿管支架置入术(双J支架或DJ支架)。治疗成功后,患者康复出院。本病例强调了即使在看似典型的EPN表现中也需考虑罕见病因的重要性。我们的病例很独特,因为患者感染了非白色念珠菌,并发无尿性急性肾损伤和糖尿病控制不佳。