Alet Matías J, Bertoni Hernán, Ameriso Sebastián F
Centro Integral de Neurología Vascular, FLENI, Buenos Aires, Argentina. E-mail:
Terapia Endovascular e Intervencionismo Oncológico, FLENI, Buenos Aires, Argentina.
Medicina (B Aires). 2024;84(2):351-355.
Paradoxical embolism due to an isolated pulmonary arteriovenous malformation (PAVM) is a rare cause of ischemic stroke. PAVMs are abnormal high-flow connections between pulmonary arteries and veins, diverting deoxygenated blood into the systemic circulation and they represent a less common source of paradoxical embolisms, especially in young individuals. Endovascular embolization is the preferred treatment for clinically significant PAVMs. We present the case of a 34-year-old woman with a left thalamic ischemic stroke. Severe contrast passage was detected in cerebral arteries through transcranial Doppler. Intracardiac ultrasound did not reveal a patent foramen ovale, prompting further investigation with pulmonary CT angiography, confirming the presence of PAVM. The patient underwent successful endovascular treatment. It is essential to consider PAVM in the etiological diagnosis of ischemic stroke, especially in young patients with signs of abnormal right-to-left communication. Periodic follow-up imaging is recommended to assess potential recurrence or changes in PAVM, emphasizing the importance of appropriate management of these malformations.
孤立性肺动静脉畸形(PAVM)所致反常栓塞是缺血性卒中的罕见病因。PAVM是肺动脉与静脉之间异常的高流量连接,使脱氧血液分流至体循环,是反常栓塞较不常见的来源,尤其是在年轻个体中。血管内栓塞是具有临床意义的PAVM的首选治疗方法。我们报告一例34岁女性左丘脑缺血性卒中病例。经颅多普勒检查发现脑动脉有严重造影剂通过。心内超声未发现卵圆孔未闭,促使进一步行肺CT血管造影检查,证实存在PAVM。该患者接受了成功的血管内治疗。在缺血性卒中的病因诊断中,尤其是在有异常右向左分流迹象的年轻患者中,必须考虑PAVM。建议定期进行随访成像以评估PAVM的潜在复发或变化,强调对这些畸形进行适当管理的重要性。