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探索新型冠状病毒肺炎与尿酸水平的关系,重点关注痛风患者:一项范围综述

Exploring the Relationship of SARS-CoV-2 and Uric Acid Levels With a Focus on Gout Patients: A Scoping Review.

作者信息

Patel Hemangi, Basra Mahi, Muralidhar Rohit, Demory Beckler Michelle, Kesselman Marc M

机构信息

Sports Medicine, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Fort Lauderdale, USA.

Osteopathic Medicine, Nova Southeastern University, Clearwater, USA.

出版信息

Cureus. 2024 Mar 28;16(3):e57138. doi: 10.7759/cureus.57138. eCollection 2024 Mar.

DOI:10.7759/cureus.57138
PMID:38686242
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11057641/
Abstract

Rheumatic diseases are a group of conditions including arthritis and various other conditions that can lead to chronic inflammation within the musculoskeletal system, which can have negative effects on soft tissues, bones, muscles, joints, and connective tissue. One form of arthritis is gout, which is an inflammatory condition in which urate acid crystals build up in joints. Gout is associated with joint swelling, pain, redness, and joint mobility issues. Early diagnosis and treatment are essential to prevent joint degradation and other adverse complications. The condition has been shown to increase the incidence of diseases outside the musculoskeletal system, including the renal and cardiovascular systems. Comorbid conditions associated with gout include but are not limited to type 2 diabetes mellitus (T2DM), hypertension, hyperlipidemia, chronic kidney disease, cardiovascular disease, and heart failure. This systematic review aims to provide insight into the relationship between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, uric acid levels, and gout.

摘要

风湿性疾病是一组病症,包括关节炎和各种其他病症,这些病症可导致肌肉骨骼系统内的慢性炎症,对软组织、骨骼、肌肉、关节和结缔组织产生负面影响。关节炎的一种形式是痛风,这是一种炎症性病症,其中尿酸晶体在关节中积聚。痛风与关节肿胀、疼痛、发红和关节活动问题有关。早期诊断和治疗对于预防关节退化和其他不良并发症至关重要。已证明该病症会增加肌肉骨骼系统以外疾病的发病率,包括肾脏和心血管系统疾病。与痛风相关的合并症包括但不限于2型糖尿病(T2DM)、高血压、高脂血症、慢性肾病、心血管疾病和心力衰竭。本系统评价旨在深入了解严重急性呼吸综合征冠状病毒2(SARS-CoV-2)感染、尿酸水平与痛风之间的关系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c619/11057641/25d585c4247d/cureus-0016-00000057138-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c619/11057641/0124f31f0fe3/cureus-0016-00000057138-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c619/11057641/81e7336fe1f5/cureus-0016-00000057138-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c619/11057641/25d585c4247d/cureus-0016-00000057138-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c619/11057641/0124f31f0fe3/cureus-0016-00000057138-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c619/11057641/81e7336fe1f5/cureus-0016-00000057138-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c619/11057641/25d585c4247d/cureus-0016-00000057138-i03.jpg

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本文引用的文献

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Gout incidence and management during the COVID-19 pandemic in England, UK: a nationwide observational study using OpenSAFELY.英国英格兰在 COVID-19 大流行期间的痛风发病率和管理:一项利用 OpenSAFELY 的全国性观察性研究。
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高尿酸血症与 COVID-19 住院患者不良结局的关系。
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Incidence of rheumatic diseases during the COVID-19 pandemic in South Korea.韩国 COVID-19 大流行期间风湿性疾病的发病率。
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Outcomes of COVID-19 in people with rheumatic and musculoskeletal disease in Ireland over the first 2 years of the pandemic.爱尔兰大流行前 2 年风湿和肌肉骨骼疾病患者的 COVID-19 结局。
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Uric acid as a prognostic predictor in COVID-19.尿酸作为新冠病毒肺炎的预后预测指标
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Gout and Excess Risk of Severe SARS-CoV-2 Infection Among Vaccinated Individuals: A General Population Study.痛风与接种疫苗人群中严重 SARS-CoV-2 感染的超额风险:一项基于普通人群的研究。
Arthritis Rheumatol. 2023 Jan;75(1):122-132. doi: 10.1002/art.42339. Epub 2022 Nov 30.
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Characteristics and Outcomes of People With Gout Hospitalized Due to COVID-19: Data From the COVID-19 Global Rheumatology Alliance Physician-Reported Registry.因COVID-19住院的痛风患者的特征与结局:来自COVID-19全球风湿病联盟医生报告注册库的数据。
ACR Open Rheumatol. 2022 Nov;4(11):948-953. doi: 10.1002/acr2.11495. Epub 2022 Aug 24.
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U-shaped association between abnormal serum uric acid levels and COVID-19 severity: reports from the Japan COVID-19 Task Force.血清尿酸水平异常与 COVID-19 严重程度之间的 U 型关联:来自日本 COVID-19 工作组的报告。
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Clinical outcomes of COVID-19 patients with rheumatic diseases: a retrospective cohort study and synthesis analysis in Wuhan, China.COVID-19 患者合并风湿病的临床结局:一项中国武汉的回顾性队列研究和综合分析。
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