Thomsen Mathias Sinkbæk, Melchiors Birgitte Bech, Garvey Lene Heise, Jessen Christian
Bedøvelse, Operation og Intensiv, Regionshospital Horsens.
Dansk Anæstesi Allergi Center, Allergisygdomme Klinik 1, Afdeling for Allergi, Hud- og Kønssygdomme, Københavns Universitetshospital - Gentofte Hospital.
Ugeskr Laeger. 2024 Apr 22;186(17). doi: 10.61409/V11230746.
Perioperative anaphylaxis is rare and the diagnosis is difficult to distinguish from normal side effects from anaesthesia. Anaesthetists should be able to diagnose anaphylaxis and treat promptly with adrenaline and fluids. Allergy investigation should be performed subsequently. This is a case report of perioperative anaphylaxis to propofol. Propofol contains refined soya oil and egg lecithin, but no connection between allergy to soy, egg or peanut and allergy to propofol has been proven, and international guidelines recommend that propofol can be used in patients with these food allergies.
围手术期过敏反应罕见,其诊断难以与麻醉的正常副作用相区分。麻醉医生应能够诊断过敏反应并立即用肾上腺素和液体进行治疗。随后应进行过敏调查。这是一例对丙泊酚发生围手术期过敏反应的病例报告。丙泊酚含有精制大豆油和蛋黄卵磷脂,但大豆、鸡蛋或花生过敏与丙泊酚过敏之间尚无已证实的关联,国际指南建议丙泊酚可用于有这些食物过敏的患者。