Soltani Hedieh, Faraji Fatemeh, Khabiri Saba, Davoodzadeh Mona, Hashemi Seyedeh Hamideh, Bagherpour Javad Zebarjadi
School of Medicine, Alborz University of Medical Sciences, Karaj, Iran.
Department of Anesthestetics, Shahid Madani Hospital, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran.
Int J Surg Case Rep. 2024 Jun;119:109655. doi: 10.1016/j.ijscr.2024.109655. Epub 2024 Apr 20.
Heterotopic ossification (HO) develops when bone formation appears in soft tissues, usually after an injury or major surgery. Timely and accurately diagnosing of this rare event is essential due to the possibility of misdiagnosis as a maintained foreign body, infection, incisional neoplastic recurrence, and metastatic or primary neoplasms.
In this study, we present a 57-year-old man who was operated for peritonitis due to perforated appendicitis, and an asymptomatic HO was accidentally found on an incisional line of previous open prostatectomy about 5 years earlier due to benign prostatic hyperplasia. A bone density lesion was seen in the fascia and on the incisional scar of previous surgery.
HO rarely occurs within an abdominal incision due to surgery. It is reported only within vertical midline incisions and mainly within the first year after the operation. Imaging confirms the diagnosis of HO in previous abdominal surgery scars, which reveals dense vertical calcification along the previous incisional scar. In the case of HO, the exclusive effective management is the entire surgical excision with primary closure, and NSAIDs are the preventive choices.
HO should be considered in patients presenting with discomfort or palpable mass or even asymptomatic patients with previous abdominal surgeries besides considering relative history such as surgical complications or neoplasms.
异位骨化(HO)是指在软组织中出现骨形成,通常发生在受伤或大手术后。由于可能被误诊为残留异物、感染、切口肿瘤复发以及转移性或原发性肿瘤,及时准确地诊断这一罕见情况至关重要。
在本研究中,我们报告了一名57岁男性,因穿孔性阑尾炎接受腹膜炎手术,意外发现其在约5年前因良性前列腺增生接受开放性前列腺切除术的切口线上有一处无症状的异位骨化。在筋膜和既往手术的切口瘢痕处可见骨密度病变。
因手术导致的HO很少出现在腹部切口中。仅在垂直中线切口内有报道,且主要发生在术后第一年内。影像学检查可确诊既往腹部手术瘢痕处的HO,表现为沿既往切口瘢痕的致密垂直钙化。对于HO,唯一有效的治疗方法是完整手术切除并一期缝合,非甾体抗炎药是预防的选择。
对于出现不适或可触及肿块的患者,甚至是既往有腹部手术史的无症状患者,除考虑手术并发症或肿瘤等相关病史外,还应考虑异位骨化的可能。