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[肺肉瘤样癌免疫治疗的进展]

[Advances in immunotherapy for pulmonary sarcomatoid carcinoma].

作者信息

Wei Y, Chen C, Xie Y F, Huang J A

机构信息

The First Affiliated Hospital of Soochow University, Suzhou 215000, China.

出版信息

Zhonghua Jie He He Hu Xi Za Zhi. 2024 May 12;47(5):480-484. doi: 10.3760/cma.j.cn112147-20231118-00318.

Abstract

Pulmonary sarcomatoid carcinoma (PSC) is a rare, poorly differentiated non-small cell lung cancer (NSCLC) that contains sarcomatoid components or sarcomatoid differentiation, and accounts for less than 1% of all lung tumors. Compared to other types of NSCLC, PSC has more invasive biological behavior, is prone to metastasis, and has a higher recurrence rate after early surgery. Its greater resistance to traditional treatments leads to a poorer prognosis compared to other NSCLCs. Immunotherapy offers the possibility of long-term survival for PSC patients.

摘要

肺肉瘤样癌(PSC)是一种罕见的、低分化非小细胞肺癌(NSCLC),含有肉瘤样成分或肉瘤样分化,占所有肺部肿瘤的比例不到1%。与其他类型的NSCLC相比,PSC具有更强的侵袭性生物学行为,易于转移,早期手术后复发率更高。与其他NSCLC相比,其对传统治疗的更大耐药性导致预后更差。免疫疗法为PSC患者提供了长期生存的可能性。

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