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西班牙裔人群对皮肤癌临床试验的认知、态度和看法。

Knowledge, Attitudes, and Perceptions of Skin Cancer Clinical Trials in the Hispanic Population.

作者信息

Andrade Luis F, Lalama Maria J, Choragudi Siri, Maisonet Jezabel, Ayala Juan, Figueroa Cesar, Lopez Liz C, Tavarez Lauren, Kirsner Robert S, Strasswimmer John

机构信息

Dermatology, Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, USA.

Medicine, Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, USA.

出版信息

Cureus. 2024 Apr 2;16(4):e57480. doi: 10.7759/cureus.57480. eCollection 2024 Apr.

Abstract

OBJECTIVE

To determine the factors that might limit Hispanic patients from participating in dermatological clinical trials.

METHODS

From January 2022 to July 2022, we administered a 31-item, in-person questionnaire to patients recruited in the waiting area of the Caridad Center, one of the largest free clinics in the United States with a predominately Hispanic population, and a nearby private primary care clinic.

RESULTS

Overall, Hispanic patients agreed significantly more with statements in the domain of attitude and behavioral beliefs compared to non-Hispanic survey respondents. The Hispanic ethnicity was associated with increased odds of agreeing with the following statements: "My community would really benefit from skin cancer clinical trials" (OR=0.52; 95% CI 0.30, 0.92), "My participation in a skin cancer study would be very good" (OR=0.59; 95% CI 0.35, 0.99), and "I like to do good for others" (OR=0.41; 95% CI 0.22, 0.77).

CONCLUSION

While the United States population is composed of 18.5% Hispanics, they only account for 1% of patients enrolled in clinical trials. This study helps identify potential motivational factors for Hispanic patients to participate in skin cancer clinical trials.

摘要

目的

确定可能限制西班牙裔患者参与皮肤科临床试验的因素。

方法

2022年1月至2022年7月,我们对在美国最大的免费诊所之一卡里达中心候诊区招募的患者进行了一项包含31个项目的现场问卷调查,该诊所主要服务西班牙裔人群,同时还对附近一家私立初级保健诊所的患者进行了调查。

结果

总体而言,与非西班牙裔调查对象相比,西班牙裔患者在态度和行为信念方面的陈述上表示更认同。西班牙裔与认同以下陈述的几率增加相关:“我的社区将真正从皮肤癌临床试验中受益”(OR = 0.52;95%置信区间0.30,0.92),“我参与皮肤癌研究将非常有益”(OR = 0.59;95%置信区间0.35,0.99),以及“我喜欢为他人做好事”(OR = 0.41;95%置信区间0.22,0.77)。

结论

虽然美国人口中有18.5%是西班牙裔,但他们仅占参与临床试验患者的1%。本研究有助于确定西班牙裔患者参与皮肤癌临床试验的潜在激励因素。

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本文引用的文献

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