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重症肌无力危象合并应激性心肌病并伴有休克

Myasthenic Crisis and Concomitant Takotsubo Syndrome Complicated by Shock.

作者信息

Omiya Moeko, Morii Yusuke, Mukai Masako, Mitsuhashi Yuya, Kato Ken, Isogai Toshiaki

机构信息

Department of Emergency and General Medicine, Tokyo Metropolitan Tama Medical Center, Japan.

Department of Cardiology, Tokyo Metropolitan Tama Medical Center, Japan.

出版信息

Intern Med. 2024 Dec 15;63(24):3383-3387. doi: 10.2169/internalmedicine.3306-23. Epub 2024 May 9.

Abstract

A man in his 80s with myasthenia gravis (MG) developed dysmobility and chest discomfort. An electrocardiogram revealed ST-segment elevation, and coronary angiography revealed Takotsubo syndrome (TTS). He experienced myasthenic crisis that required ventilation and shock that was refractory to vasopressors and required intra-aortic balloon pump (IABP) insertion. He was managed conservatively without MG-specific treatment until his hemodynamics improved. On hospital day 6, he was weaned from IABP. MG is a high-risk condition for TTS, and TTS with myasthenic crisis (MC) is associated with high mortality. We successfully managed this case of TTS with MC with intubation and IABP, without MG-specific treatment.

摘要

一名80多岁的重症肌无力(MG)患者出现活动障碍和胸部不适。心电图显示ST段抬高,冠状动脉造影显示为应激性心肌病(TTS)。他经历了肌无力危象,需要通气支持,还出现了对血管加压药难治的休克,需要插入主动脉内球囊反搏(IABP)。在血流动力学改善之前,他接受了保守治疗,未进行MG特异性治疗。住院第6天,他撤离了IABP。MG是发生TTS的高危疾病,伴有肌无力危象(MC)的TTS与高死亡率相关。我们通过插管和IABP成功治疗了这例伴有MC的TTS患者,未进行MG特异性治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1611/11729183/283451eaee35/1349-7235-63-3383-g001.jpg

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