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不同近视度数的小切口透镜切除术术后角膜后表面高度的变化。

Changes in posterior corneal elevation after small incision lenticule extraction for different myopic diopters.

作者信息

Sun Xiao-Tong, Zhang Yang, Mei Xiao-Kun, Zheng Nan-Nan, Niu Ling-Zhi, Qu Xiao-Li, Song Ai-Ping, Zhuo Jian

机构信息

Department of Ophthalmology, the First Affiliated Hospital of Shandong First Medical University, Shandong Provincial Qianfoshan Hospital, Jinan 250014, Shandong Province, China.

出版信息

Int J Ophthalmol. 2024 Mar 18;17(3):491-498. doi: 10.18240/ijo.2024.03.11. eCollection 2024.

Abstract

AIM

To study the changes and effect factors of posterior corneal surface after small incision lenticule extraction (SMILE) with different myopic diopters.

METHODS

Ninety eyes of 90 patients who underwent SMILE were included in this retrospective study. Patients were allocated into three groups based on the preoperative spherical equivalent (SE): low myopia (SE≥-3.00 D), moderate myopia (-3.00 D>SE>-6.00 D) and high myopia (SE≤-6.00 D). Posterior corneal surfaces were measured by a Scheimpflug camera preoperatively and different postoperative times (1wk, 1, 3, 6mo, and 1y). Posterior mean elevation (PME) at 25 predetermined points of 3 concentric circles (2-, 4-, and 6-mm diameter) above the best fit sphere was analyzed.

RESULTS

All surgeries were completed uneventfully and no ectasia was found through the observation. The difference of myopia group was significant at the 2-mm ring at 1 and 3mo postoperatively (1mo: =0.017; 3mo: =0.018). The effect of time on ΔPME was statistically significant (2-mm ring: =0.001; 4-mm ring: <0.001; 6-mm ring: <0.001). The effect of different corneal locations on ΔPME was significant except 1wk postoperatively (1mo: =0.000; 3mo: =0.000; 6mo: =0.001; 1y: =0.001). Posterior corneal stability was linearly correlated with SE, central corneal thickness, ablation depth, residual bed thickness, percent ablation depth and percent stromal bed thickness.

CONCLUSION

The posterior corneal surface changes dynamically after SMILE. No protrusion is observed on the posterior corneal surface in patients with different degrees of myopia within one year after surgery. SMILE has good stability, accuracy, safety and predictability.

摘要

目的

研究不同近视度数患者在小切口透镜切除术(SMILE)后角膜后表面的变化及影响因素。

方法

本回顾性研究纳入90例行SMILE手术的患者的90只眼。根据术前等效球镜度(SE)将患者分为三组:低度近视(SE≥-3.00 D)、中度近视(-3.00 D>SE>-6.00 D)和高度近视(SE≤-6.00 D)。术前及术后不同时间点(1周、1、3、6个月和1年)用眼前节分析系统测量角膜后表面。分析在最佳拟合球面上方3个同心圆(直径2、4和6 mm)的25个预定点处的后平均高度(PME)。

结果

所有手术均顺利完成,观察期间未发现角膜扩张。近视组在术后1个月和3个月时2 mm环处差异有统计学意义(1个月:=0.017;3个月:=0.018)。时间对ΔPME的影响有统计学意义(2 mm环:=0.001;4 mm环:<0.001;6 mm环:<0.001)。除术后1周外,不同角膜位置对ΔPME的影响有统计学意义(1个月:=0.000;3个月:=0.000;6个月:=0.001;1年:=0.001)。角膜后表面稳定性与SE、中央角膜厚度、切削深度、剩余床厚度、切削深度百分比和基质床厚度百分比呈线性相关。

结论

SMILE术后角膜后表面动态变化。术后1年内不同近视程度患者角膜后表面均未观察到突出。SMILE具有良好的稳定性、准确性、安全性和可预测性。

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