Medical School, Department of Pediatrics, Surgical Division, University of Pécs, 7 József Attila Street, Pécs, 7623, Hungary.
Department of Paediatric Surgery, Petz Aladár University Teaching Hospital, 2-4 Vasvári Pál Street, Győr, 9023, Hungary.
Pediatr Surg Int. 2024 May 10;40(1):131. doi: 10.1007/s00383-024-05714-z.
To evaluate the urodynamic changes in patients who have undergone colocystoplasty (CCP), gastrocystoplasty (GCP) and ileocystoplasty (ICP) in a retrospective study. Changes in urinary continence, incidence of pathologic contractions before and after augmentation, alterations of urodynamic parameters were also examined.
Eighty-four patients were included in the study who underwent bladder augmentation between 1987 and 2017. Group I: 35 patients with CCP. Group II: 18 patients with GCP. Group III: 31 patients with ICP. Cystometry was performed at 3, 6, and every 12 months, then biannually after augmentation. Pre- and postoperative urodynamic changes were analysed statistically.
In Group I, two patients and in Group III, one patient remained incontinent after CCP and ICP. Bladder capacity increased significantly, maximal intra-vesical pressure decreased and compliance improved in all groups (p < 0.001). Postoperative studies showed pathologic contractions in the augmented bladder in half of the patients with GCP, in 43% of patients after CCP and 26% of patients with ICP.
From the urodynamic point of view, ileum is the most adequate option in the long term. Contractions after augmentation might be caused by the remaining peristalsis of the detubularised segment. Further investigations are needed to evaluate pathologic contractions that remained after detubularisation.
在一项回顾性研究中,评估接受结肠代膀胱术(CCP)、胃代膀胱术(GCP)和回肠代膀胱术(ICP)的患者的尿动力学变化。还检查了尿控、增强前后病理性收缩的发生率以及尿动力学参数的改变。
本研究纳入了 1987 年至 2017 年间接受膀胱扩大术的 84 名患者。组 I:35 例 CCP 患者。组 II:18 例 GCP 患者。组 III:31 例 ICP 患者。在扩大术后 3、6 和 12 个月以及术后每 12 个月进行膀胱测压检查,然后每 6 个月进行一次。对术前和术后的尿动力学变化进行统计学分析。
在组 I 中,2 例患者和在组 III 中,1 例患者在接受 CCP 和 ICP 后仍存在尿失禁。所有组的膀胱容量均显著增加,最大膀胱内压降低,顺应性改善(p < 0.001)。术后研究显示,GCP 中一半的患者、CCP 后 43%的患者和 ICP 后 26%的患者的增强膀胱存在病理性收缩。
从尿动力学的角度来看,回肠是长期来看最理想的选择。增强后出现的收缩可能是由于去管化段残留的蠕动引起的。需要进一步研究以评估去管化后仍存在的病理性收缩。