Department of Emergency Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa.
Department of Emergency Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa.
J Emerg Med. 2024 Jun;66(6):e704-e713. doi: 10.1016/j.jemermed.2024.03.002. Epub 2024 Mar 16.
The use of potentially inappropriate medications (PIMs) is considered an important quality indicator for older adults seen in the ambulatory care setting.
To evaluate the pattern of potentially inappropriate medication (PIMs) use as specified in the Beers Criteria, for older adults during emergency department (ED) visits in the United States.
Using data from the National Hospital Ambulatory Care Survey (NHAMCS) we identified older adults (age 65 or older) discharged home from an ED visit in 2019. We defined PIMs as those with an 'avoid' recommendation under the American Geriatrics Society (AGS) 2019 Beers Criteria in older adults. Logistic regression models were used to assess demographic, clinical, and hospital factors associated with the use of any PIMs upon ED discharge.
Overall, 5.9% of visits by older adults discharged from the ED included administration or prescriptions for PIMs. Among those who received any PIMs, 25.5% received benzodiazepines, 42.5 % received anticholinergics, 1.4% received nonbenzodiazepine hypnotics, and 0.5% received barbiturates. A multivariable model showed statistically significant associations for age 65 to 74 (OR 1.91, 95% CI 1.39-2.62 vs. age >=75), dementia (OR 0.45, 95% CI 0.21-0.95), lower immediacy (OR 2.45, 95% CI 1.56-3.84 vs. higher immediacy), and Northeastern rural region (OR 0.34, 95% CI 0.21-0.55 vs. Midwestern rural).
We found that younger age and lower immediacy were associated with increased prescriptions of PIMs for older adults seen, while dementia and Northeastern rural region was associated with reduced use of PIMs seen and discharged from EDs in United States.
在门诊环境中,使用潜在不适当药物(PIMs)被认为是评估老年患者的一个重要质量指标。
评估美国急诊科(ED)就诊的老年患者使用《Beers 标准》中规定的潜在不适当药物(PIMs)的模式。
我们利用来自全国医院门诊医疗调查(NHAMCS)的数据,确定了在 2019 年从 ED 出院的老年患者(年龄≥65 岁)。我们将符合美国老年医学会(AGS)2019 年《Beers 标准》中“避免”建议的药物定义为 PIMs。采用逻辑回归模型评估与 ED 出院时使用任何 PIMs 相关的人口统计学、临床和医院因素。
总体而言,5.9%的 ED 老年患者出院时接受了 PIMs 的管理或处方。在接受任何 PIMs 的患者中,25.5%接受了苯二氮䓬类药物,42.5%接受了抗胆碱能药物,1.4%接受了非苯二氮䓬类催眠药,0.5%接受了巴比妥类药物。多变量模型显示,年龄 65 至 74 岁(比值比 [OR] 1.91,95%置信区间 [CI] 1.39-2.62 比年龄≥75 岁)、痴呆(OR 0.45,95%CI 0.21-0.95)、低紧急性(OR 2.45,95%CI 1.56-3.84 比高紧急性)和东北农村地区(OR 0.34,95%CI 0.21-0.55 比中西部农村)与 PIMs 的使用显著相关。
我们发现,年龄较小和紧急程度较低与老年患者 ED 就诊时 PIMs 的处方增加有关,而痴呆和东北农村地区与美国 ED 就诊和出院的 PIMs 使用减少有关。