Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.
Division of Clinical Trials and Biostatistics, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota.
J Arthroplasty. 2024 Sep;39(9S1):S97-S100. doi: 10.1016/j.arth.2024.05.016. Epub 2024 May 11.
Our previously reported randomized clinical trial of direct anterior approach (DAA) versus mini-posterior approach (MPA) total hip arthroplasty showed slightly faster initial recovery for patients who had a DAA and no differences in complications or clinical or radiographic outcomes beyond 8 weeks. The aims of the current study were to determine if early advantages of DAA led to meaningful clinical differences beyond 5 years and to identify differences in midterm complications.
Of the 101 original patients, 93 were eligible for follow-up at a mean of 7.5 years (range, 2.1 to 10). Clinical outcomes were compared with Harris Hip, 12-Item Short Form Health Survey, and Hip Disability and Osteoarthritis Outcomes Scores (HOOS) scores and subscores, complications, reoperations, and revisions.
Harris Hip scores were similar (95.3 ± 6.0 versus 93.5 ± 10.3 for DAA and MPA, respectively, P = .79). The 12-Item Short Form Health Survey physical and mental scores were similar (46.2 ± 9.3 versus 46.2 ± 10.6, P = .79, and 52.3 ± 7.1 versus 55.2 ± 4.5, P = .07 in the DAA and MPA groups, respectively). The HOOS scores were similar (97.4 ± 7.9 versus 96.3 ± 6.7 for DAA and MPA, respectively, P = .07). The HOOS quality of life subscores were 96.9 ± 10.8 versus 92.3 ± 16.0 for DAA and MPA, respectively (P = .046). No clinical outcome met the minimally clinically important difference. There were 4 surgical complications in the DAA group (1 femoral loosening requiring revision, 1 dislocation treated closed, and 2 wound dehiscences requiring debridement), and 6 surgical complications in the MPA group (3 dislocations, 2 treated closed, and 1 revised to dual mobility; 2 intraoperative fractures treated with a cable; and 1 wound dehiscence treated nonoperatively).
At a mean of 7.5 years, this randomized clinical trial demonstrated no clinically meaningful differences in outcomes, complications, reoperations, or revisions between DAA and MPA total hip arthroplasty.
IV.
我们之前报道的直接前路(DAA)与小切口后路(MPA)全髋关节置换术的随机临床试验显示,DAA 组患者的初始恢复稍快,但在 8 周后并发症、临床或影像学结果无差异。本研究的目的是确定 DAA 的早期优势是否会在 5 年以上产生有意义的临床差异,并确定中期并发症的差异。
在最初的 101 名患者中,93 名符合随访条件,平均随访时间为 7.5 年(范围:2.1 至 10 年)。通过 Harris 髋关节评分、12 项简明健康调查量表(SF-12)和髋关节残疾和骨关节炎结果评分(HOOS)评分及其亚评分比较临床结果,评估并发症、再次手术和翻修情况。
Harris 髋关节评分相似(DAA 组为 95.3±6.0,MPA 组为 93.5±10.3,P=0.79)。12 项简明健康调查量表的生理和心理评分相似(DAA 组为 46.2±9.3,MPA 组为 46.2±10.6,P=0.79;DAA 组为 52.3±7.1,MPA 组为 55.2±4.5,P=0.07)。HOOS 评分相似(DAA 组为 97.4±7.9,MPA 组为 96.3±6.7,P=0.07)。HOOS 生活质量亚评分相似(DAA 组为 96.9±10.8,MPA 组为 92.3±16.0,P=0.046)。没有任何临床结果达到最小临床重要差异。DAA 组有 4 例手术并发症(1 例股骨松动需要翻修,1 例脱位经闭合治疗,2 例切口裂开需要清创),MPA 组有 6 例手术并发症(3 例脱位,2 例经闭合治疗,1 例改为双动;2 例术中骨折用电缆固定;1 例切口裂开非手术治疗)。
在平均 7.5 年的随访中,这项随机临床试验表明,直接前路与小切口后路全髋关节置换术在结果、并发症、再次手术或翻修方面没有临床意义上的差异。
IV 级。