Suppr超能文献

[AL型淀粉样变性]

[AL Amyloidosis].

作者信息

Ueda Mitsuharu

机构信息

Department of Neurology, Graduate School of Medical Sciences, Kumamoto University.

出版信息

Brain Nerve. 2024 May;76(5):583-587. doi: 10.11477/mf.1416202647.

Abstract

AL amyloidosis, derived from amyloidogenic immunoglobulin light chains, is a common type of systemic amyloidosis. Peripheral neuropathy has been identified in 10%-40% of patients with systemic AL amyloidosis. Definitive diagnosis requires tissue biopsies, including skin, fat, and gastrointestinal samples, as well as amyloid typing. Disease-modifying therapies have been shown to improve patient survival and prevent progressive organ dysfunction.

摘要

AL淀粉样变性由淀粉样免疫球蛋白轻链衍生而来,是系统性淀粉样变性的常见类型。10%-40%的系统性AL淀粉样变性患者已被确诊患有周围神经病变。明确诊断需要进行组织活检,包括皮肤、脂肪和胃肠道样本,以及淀粉样蛋白分型。已证明疾病修饰疗法可提高患者生存率并预防进行性器官功能障碍。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验