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欣曼综合征:一种具有神经源性膀胱样症状的罕见病症。

Hinman Syndrome: A Rare Entity With Neurogenic Bladder-Like Symptoms.

作者信息

Gampala Sravani, Alkukhun Leen, Khan Zohaib, Hanumaiah Ravikumar, Majmudar Anand

机构信息

Radiology, State University of New York (SUNY) Upstate Medical University, Syracuse, USA.

出版信息

Cureus. 2024 Apr 13;16(4):e58191. doi: 10.7759/cureus.58191. eCollection 2024 Apr.

DOI:10.7759/cureus.58191
PMID:38741815
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11089924/
Abstract

Hinman syndrome, as is the case with many other rare conditions, is a disease very commonly under-considered or missed in the diagnosis of patients with the presenting symptoms. Clinical and radiographic manifestations of the condition are easily confused with neurogenic bladder without proper history collection and neurological examination. Patients typically present with symptoms including enuresis, urinary retention, reoccurring urinary tract infections, and encopresis. Imaging often shows hydroureteronephrosis and marked bladder wall thickening. While these signs are characteristic of neurogenic bladder, routine neurologic examinations and MRIs of patients with Hinman syndrome often show normal results, and their condition is currently thought to be an acquired behavioral and psychological disorder, often associated with abnormal family dynamics. We present the case of a 14-year-old boy, who presented to the emergency department with nausea, bilateral flank pain, and urinary retention. The patient had an over seven-year history of recurrent urinary tract infections (UTI) and intermittent encopresis and followed up with different providers. Due to the patient's extensive history and the failure of previous treatments, he was evaluated for causes of neurogenic bladder, but the MRI of the lumbar spine was normal. Fluoroscopic voiding cystourethrogram (VCUG) was ordered and demonstrated abnormal and trabeculated contour of the urinary bladder with bilateral vesicoureteral reflux consistent with the diagnosis of Hinman syndrome.

摘要

欣曼综合征与许多其他罕见疾病一样,在诊断有相关症状的患者时,是一种常被忽视或漏诊的疾病。如果没有适当的病史采集和神经系统检查,该疾病的临床和影像学表现很容易与神经源性膀胱混淆。患者通常表现出包括遗尿、尿潴留、反复尿路感染和大便失禁等症状。影像学检查常显示肾盂输尿管积水和膀胱壁明显增厚。虽然这些体征是神经源性膀胱的特征,但欣曼综合征患者的常规神经系统检查和磁共振成像(MRI)结果通常正常,目前认为其病情是一种后天获得性行为和心理障碍,常与异常的家庭动态有关。我们报告一例14岁男孩的病例,他因恶心、双侧胁腹疼痛和尿潴留到急诊科就诊。该患者有超过七年的反复尿路感染(UTI)和间歇性大便失禁病史,并曾在不同医疗机构就诊。由于患者病史复杂且先前治疗无效,对其进行了神经源性膀胱病因评估,但腰椎MRI结果正常。于是安排了荧光透视排尿膀胱尿道造影(VCUG)检查,结果显示膀胱轮廓异常且有小梁形成,伴有双侧膀胱输尿管反流,符合欣曼综合征的诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e45/11089924/b8d89b30f73a/cureus-0016-00000058191-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e45/11089924/ced7aad7aa82/cureus-0016-00000058191-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e45/11089924/c55ecbc242a8/cureus-0016-00000058191-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e45/11089924/bc39ecb39c27/cureus-0016-00000058191-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e45/11089924/ed53ae3b086f/cureus-0016-00000058191-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e45/11089924/7ad0cb28b1d8/cureus-0016-00000058191-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e45/11089924/6feea76cbaf6/cureus-0016-00000058191-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e45/11089924/cd262d577a8d/cureus-0016-00000058191-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e45/11089924/b8d89b30f73a/cureus-0016-00000058191-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e45/11089924/ced7aad7aa82/cureus-0016-00000058191-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e45/11089924/c55ecbc242a8/cureus-0016-00000058191-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e45/11089924/bc39ecb39c27/cureus-0016-00000058191-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e45/11089924/ed53ae3b086f/cureus-0016-00000058191-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e45/11089924/7ad0cb28b1d8/cureus-0016-00000058191-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e45/11089924/6feea76cbaf6/cureus-0016-00000058191-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e45/11089924/cd262d577a8d/cureus-0016-00000058191-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e45/11089924/b8d89b30f73a/cureus-0016-00000058191-i08.jpg

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本文引用的文献

1
Nonneuropathic Neuropathic Bladder-Is it Really Nonneuropathic?非神经性神经性膀胱——它真的是非神经性的吗?
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Vesical and Ureteral Damage from Voiding Dysfunction in Boys Without Neurologic or Obstructive Disease.无神经或梗阻性疾病男孩排尿功能障碍所致膀胱和输尿管损伤
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Distention of the posterior urethra: association with nonneurogenic neurogenic bladder (Hinman syndrome).后尿道扩张:与非神经源性神经源性膀胱(欣曼综合征)的关联。
Radiology. 1992 Oct;185(1):113-7. doi: 10.1148/radiology.185.1.1523292.