Apeiranthiti Aikaterini, Vanniere Fleur, Bayoumy Karim, Christofis Melissa, Serena Andrea, Mosimann Valerie, Abdelhamid Karim, Papadopoulos Sotirios, Nguyen-Ngoc Tu, Bouchaab Hasna, Peters Solanges, Mederos Nuria
Service d'oncologie médicale, Département d'oncologie, Centre hospitalier universitaire vaudois, 1011 Lausanne.
Rev Med Suisse. 2024 May 15;20(874):973-977. doi: 10.53738/REVMED.2024.20.874.973.
Lung cancer is notoriously known for its predisposition to metastasize to the bones. Diagnostic tools, including positron emission tomography coupled with computed tomography, offer increased sensitivity in detecting bone infiltration. Management strategies encompass a multidisciplinary approach, including pharmacological pain management, anti-resorptive therapy, radiotherapy, interventional techniques, and surgery. This article provides an in-depth analysis of the incidence and distribution of bone metastases, skeletal-related events (SRE), diagnostic imaging techniques, and contemporary therapeutic strategies to prevent SRE. Systemic anticancer therapy and pain management, although crucial for treating BM, are not discussed in this article.
肺癌因易于转移至骨骼而臭名昭著。包括正电子发射断层扫描与计算机断层扫描相结合在内的诊断工具,在检测骨浸润方面具有更高的灵敏度。管理策略包括多学科方法,涵盖药物性疼痛管理、抗骨吸收治疗、放射治疗、介入技术和手术。本文深入分析了骨转移的发生率和分布、骨相关事件(SRE)、诊断成像技术以及预防SRE的当代治疗策略。全身抗癌治疗和疼痛管理虽然对治疗骨转移至关重要,但本文未作讨论。