Centre for Health Economics, University of York, York, UK.
Department of Infectious Disease Epidemiology, Imperial College London, London, UK.
Lancet Glob Health. 2024 Jun;12(6):e1027-e1037. doi: 10.1016/S2214-109X(24)00095-0.
Medical consumable stock-outs negatively affect health outcomes not only by impeding or delaying the effective delivery of services but also by discouraging patients from seeking care. Consequently, supply chain strengthening is being adopted as a key component of national health strategies. However, evidence on the factors associated with increased consumable availability is limited.
In this study, we used the 2018-19 Harmonised Health Facility Assessment data from Malawi to identify the factors associated with the availability of consumables in level 1 facilities, ie, rural hospitals or health centres with a small number of beds and a sparsely equipped operating room for minor procedures. We estimate a multilevel logistic regression model with a binary outcome variable representing consumable availability (of 130 consumables across 940 facilities) and explanatory variables chosen based on current evidence. Further subgroup analyses are carried out to assess the presence of effect modification by level of care, facility ownership, and a categorisation of consumables by public health or disease programme, Malawi's Essential Medicine List classification, whether the consumable is a drug or not, and level of average national availability.
Our results suggest that the following characteristics had a positive association with consumable availability-level 1b facilities or community hospitals had 64% (odds ratio [OR] 1·64, 95% CI 1·37-1·97) higher odds of consumable availability than level 1a facilities or health centres, Christian Health Association of Malawi and private-for-profit ownership had 63% (1·63, 1·40-1·89) and 49% (1·49, 1·24-1·80) higher odds respectively than government-owned facilities, the availability of a computer had 46% (1·46, 1·32-1·62) higher odds than in its absence, pharmacists managing drug orders had 85% (1·85, 1·40-2·44) higher odds than a drug store clerk, proximity to the corresponding regional administrative office (facilities greater than 75 km away had 21% lower odds [0·79, 0·63-0·98] than facilities within 10 km of the district health office), and having three drug order fulfilments in the 3 months before the survey had 14% (1·14, 1·02-1·27) higher odds than one fulfilment in 3 months. Further, consumables categorised as vital in Malawi's Essential Medicine List performed considerably better with 235% (OR 3·35, 95% CI 1·60-7·05) higher odds than other essential or non-essential consumables and drugs performed worse with 79% (0·21, 0·08-0·51) lower odds than other medical consumables in terms of availability across facilities.
Our results provide evidence on the areas of intervention with potential to improve consumable availability. Further exploration of the health and resource consequences of the strategies discussed will be useful in guiding investments into supply chain strengthening.
UK Research and Innovation as part of the Global Challenges Research Fund (Thanzi La Onse; reference MR/P028004/1), the Wellcome Trust (Thanzi La Mawa; reference 223120/Z/21/Z), the UK Medical Research Council, the UK Department for International Development, and the EU (reference MR/R015600/1).
医疗耗材缺货不仅会阻碍或延迟有效服务的提供,从而影响健康结果,还会使患者不愿寻求医疗服务。因此,供应链的加强被作为国家卫生战略的一个关键组成部分。然而,关于增加消耗品可获得性的相关因素的证据有限。
本研究使用马拉维 2018-19 年卫生设施综合评估数据,确定了与一级设施(即农村医院或有少量床位和设备简陋的手术室的卫生中心)消耗品可得性相关的因素,这些设施可进行少量手术。我们根据现有证据,使用具有二项结果变量的多水平逻辑回归模型来估计消耗品可得性(940 家设施中的 130 种消耗品)和解释变量。进一步进行亚组分析,以评估护理水平、设施所有权、消耗品的公共卫生或疾病规划分类、马拉维基本药物清单分类、消耗品是否为药物以及全国平均供应水平的效应修饰作用。
我们的研究结果表明,以下特征与消耗品的可得性呈正相关:一级 b 类设施或社区医院的消耗品可得性比一级 a 类设施或卫生中心高 64%(比值比 [OR] 1.64,95%CI 1.37-1.97);基督教健康协会和私营盈利性所有权比政府所有设施的消耗品可得性分别高 63%(1.63,1.40-1.89)和 49%(1.49,1.24-1.80);有计算机比没有计算机的消耗品可得性高 46%(1.46,1.32-1.62);药剂师管理药品订单比药品店员的消耗品可得性高 85%(1.85,1.40-2.44);离相应区域行政办公室的距离(距离区卫生办公室超过 75 公里的设施的可能性比距离 10 公里以内的设施低 21% [0.79,0.63-0.98]);在调查前 3 个月有三次药品订单满足情况比在 3 个月内有一次满足情况的消耗品可得性高 14%(1.14,1.02-1.27)。此外,在马拉维基本药物清单中被归类为重要的消耗品的可得性比其他基本或非基本消耗品高 235%(OR 3.35,95%CI 1.60-7.05),而药物的可得性比其他医疗消耗品低 79%(0.21,0.08-0.51)。
我们的研究结果提供了有关具有潜在改善消耗品可得性的干预领域的证据。进一步探讨所讨论策略的健康和资源后果,将有助于指导对供应链加强的投资。
英国研究与创新署(Thanzi La Onse;参考号 MR/P028004/1)、惠康信托基金(Thanzi La Mawa;参考号 223120/Z/21/Z)、英国医学研究理事会、英国国际发展部和欧盟(参考号 MR/R015600/1)。