对正常人语言产生过程中皮质和皮质下结构区域脑血流的观察。

Observations on regional cerebral blood flow in cortical and subcortical structures during language production in normal man.

作者信息

Wallesch C W, Henriksen L, Kornhuber H H, Paulson O B

出版信息

Brain Lang. 1985 Jul;25(2):224-33. doi: 10.1016/0093-934x(85)90082-3.

Abstract

Regional cerebral blood flow (rCBF) was studied by single photon emission computerized tomography (SPECT) of inhaled xenon-133 in six normal volunteers during various language, articulatory, and control conditions. Language production increased rCBF in predominantly left-sided cortical and subcortical areas. The involved regions were anatomically related to a left frontal area (Broca's), to both caudate nuclei, to a left thalamic/pallidal area, and bilaterally in retrorolandic areas. The failure to demonstrate lateralized retrorolandic activity is thought to reflect the complexity of the tasks.

摘要

在六名正常志愿者处于不同语言、发音及对照状态时，通过吸入氙-133的单光子发射计算机断层扫描（SPECT）研究了局部脑血流量（rCBF）。语言产生增加了主要位于左侧的皮质和皮质下区域的rCBF。所涉及的区域在解剖学上与左侧额叶区域（布洛卡区）、双侧尾状核、左侧丘脑/苍白球区域以及双侧罗兰后区域相关。未能显示出罗兰后区域的单侧化活动被认为反映了任务的复杂性。