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子宫内膜异位症患者的生育力保存:卵母细胞冷冻保存和其他技术。

Fertility preservation in women with endometriosis: Oocyte cryopreservation and other techniques.

机构信息

DINOGMI, University of Genova, Genova, Italy; IRCCS Ospedale Policlinico San Martino, Genova, Italy.

Fertilab Barcelona, Barcelona, Spain.

出版信息

Best Pract Res Clin Obstet Gynaecol. 2024 Jul;95:102503. doi: 10.1016/j.bpobgyn.2024.102503. Epub 2024 May 16.

Abstract

In recent years, advancements in cryopreservation techniques for oocytes, embryos, and ovarian tissue have enabled offering fertility preservation (FP) options to women with endometriosis. It is recommended to always conduct specialized counselling on FP, especially before considering surgical interventions for endometriosis. The decision regarding the methods of FP, the timing, and to which women affected by endometriosis these techniques should be offered are still subjects of discussion. However, several studies suggest that it can be proposed before surgical interventions for endometriosis, particularly if the patient is undergoing mono or bilateral endometrioma surgery. The most recommended technique is ovarian stimulation, followed by oocyte cryopreservation. Nevertheless, the literature contains various studies describing FP through embryo cryopreservation or the retrieval and cryopreservation of ovarian tissue.

摘要

近年来,卵母细胞、胚胎和卵巢组织的冷冻保存技术的进步,使患有子宫内膜异位症的女性能够选择进行生育力保存(FP)。建议对 FP 进行专门咨询,特别是在考虑对子宫内膜异位症进行手术干预之前。关于 FP 方法、时机以及应向哪些患有子宫内膜异位症的女性提供这些技术的决策仍在讨论中。然而,一些研究表明,在进行子宫内膜异位症的手术干预之前,可以提出这一建议,特别是如果患者正在接受单侧或双侧子宫内膜异位瘤手术。最推荐的技术是卵巢刺激,其次是卵母细胞冷冻保存。然而,文献中包含了各种通过胚胎冷冻保存或卵巢组织的获取和冷冻保存来进行 FP 的研究。

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