Department of Environmental Health Sciences, Fielding School of Public Health, University of California Los Angeles, Los Angeles, CA 90095, United States.
Department of Environmental & Occupational Health, College of Health & Human Development, California State University Northridge, Northridge, CA 91330, United States.
Ann Work Expo Health. 2024 Jul 8;68(6):581-592. doi: 10.1093/annweh/wxae034.
Leisure-time physical activity (LTPA) can reduce the risk of incident diabetes, whereas the role of occupational physical activity (OPA) in developing diabetes is still unclear due to conflicting evidence. Moreover, the joint associations of OPA and LTPA with incident diabetes among US workers have not yet been systematically examined. The objective of this study was to assess the independent and joint associations of OPA and LTPA with incident diabetes.
This prospective cohort study included 1406 workers free from diabetes at baseline (2004-2006) from the national, population-based Mid-life in the United States (MIDUS) study. Associations of OPA and LTPA at baseline with incident diabetes during 9 years of follow-up were examined using Poisson regression models. High OPA was defined based on engagement in physical demands at work, and high LTPA was defined as participation in moderate or vigorous LTPA at least once per week.
High OPA was associated with an increased risk of diabetes compared to low OPA (adjusted risk ratios and 95% confidence interval = 1.52 [1.04, 2.22]), while high LTPA was associated with a decreased risk of diabetes compared to low LTPA (0.66 [0.44, 0.97]). Diabetes risk was the highest among workers with high OPA and low LTPA (2.30 [1.30, 4.07]).
In a national, population-based prospective cohort study of US workers, high OPA was associated with an elevated risk of diabetes, while high LTPA was associated with a decreased diabetes risk. The combination of high OPA and low LTPA exhibited the greatest risk of diabetes.
休闲时间体力活动（LTPA）可降低糖尿病发病风险，而职业体力活动（OPA）在糖尿病发病中的作用尚不清楚，因为证据相互矛盾。此外，美国工人中 OPA 和 LTPA 与糖尿病发病的联合关联尚未得到系统研究。本研究旨在评估 OPA 和 LTPA 与糖尿病发病的独立和联合关联。
本前瞻性队列研究纳入了来自全国性、基于人群的美国中年生活（MIDUS）研究的 1406 名基线时无糖尿病的工人（2004-2006 年）。使用泊松回归模型检验基线时的 OPA 和 LTPA 与 9 年随访期间糖尿病发病的相关性。根据工作中体力需求的参与程度定义高 OPA，根据每周至少一次进行中度或剧烈 LTPA 定义高 LTPA。
与低 OPA 相比，高 OPA 与糖尿病发病风险增加相关（调整后的风险比和 95%置信区间=1.52[1.04, 2.22]），而高 LTPA 与糖尿病发病风险降低相关（0.66[0.44, 0.97]）。与低 LTPA 相比，高 OPA 和低 LTPA 的工人糖尿病发病风险最高（2.30[1.30, 4.07]）。
在一项针对美国工人的全国性、基于人群的前瞻性队列研究中，高 OPA 与糖尿病发病风险增加相关，而高 LTPA 与糖尿病发病风险降低相关。高 OPA 和低 LTPA 的组合表现出最大的糖尿病发病风险。
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