Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Prince of Songkla University, Hat Yai, Songkhla, 90112, Thailand.
Oral Maxillofac Surg. 2024 Sep;28(3):1327-1338. doi: 10.1007/s10006-024-01262-x. Epub 2024 May 24.
This study aimed to investigate the viability of free gingival grafts (FGG) and assess clinical and radiographic changes in the alveolar ridge following socket seal surgery with or without freeze-dried bone allograft (FDBA).
Twenty-eight anterior and premolar tooth extractions were randomly allocated to 2 groups: socket graft of FDBA sealed with FGG (n = 15) and control with empty sockets sealed solely with FGG (n = 13). Photographs taken at 3, 7, 14, and 30 days post-surgery assessed FGG viability. Alveolar ridge volume was clinically evaluated via intraoral scanners before surgery and at 1 and 3 months post-surgery. CBCT scans taken immediately post-surgery and 3 months later assessed alveolar ridge dimensions.
FGG viability in both groups increased from day 3 and reached the maximum score on day 14. Alveolar ridge volume reduction at 3 months in the FDBA group was comparable to the control group. Buccal alveolar bone height reduction was significantly higher in the FDBA group than the control group, while palatal alveolar bone height was comparable. Alveolar bone width reduction was evident but not statistically significant between the groups. The FDBA group exhibited a significant alteration in bone volume compared to the control group.
Viability of FGG was not affected by graft filling materials. Sealing the socket with FGG effectively preserved socket integrity and ridge volume in minor socket defects using either graft filling material or not. This study was registered on 4 January 2021 on Thai Clinical Trials Registry (TCTR20210104001).
本研究旨在探讨游离龈瓣移植(FGG)的可行性,并评估在使用或不使用冻干骨移植物(FDBA)进行牙槽窝封闭手术后牙槽嵴的临床和影像学变化。
28 例前牙和前磨牙拔牙被随机分配到 2 组:用 FGG 封闭 FDBA 牙槽窝移植(n=15)和单纯用 FGG 封闭空牙槽窝的对照组(n=13)。术后 3、7、14 和 30 天拍摄的照片评估 FGG 的存活率。使用口内扫描仪在术前和术后 1 个月和 3 个月评估牙槽嵴体积。术后即刻和 3 个月后行 CBCT 扫描评估牙槽嵴宽度。
两组的 FGG 存活率均从第 3 天开始增加,并在第 14 天达到最大值。FDBA 组在 3 个月时牙槽嵴体积减少与对照组相当。FDBA 组颊侧牙槽骨高度减少显著高于对照组,而腭侧牙槽骨高度相当。牙槽骨宽度减少在两组间均明显但无统计学意义。FDBA 组与对照组相比,骨量有明显改变。
FGG 的存活率不受移植物填充材料的影响。用 FGG 封闭牙槽窝可有效保持牙槽窝的完整性和牙槽嵴体积,无论使用哪种移植物填充材料或不使用。本研究于 2021 年 1 月 4 日在泰国临床试验注册中心(TCTR20210104001)注册。