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克罗恩病与右半结肠癌右半结肠切除术后结局的比较:一项回顾性队列研究

Comparison of Post-Operative Outcomes of Right Colectomy between Crohn's Disease and Adenocarcinoma of the Right Colon: A Retrospective Cohort Study.

作者信息

Bursztyn Naama, Slomowitz Edden, Assaf Dan, Yahia Ehab Haj, Kent Ilan, Wasserberg Nir, Avital Shmuel, White Ian

机构信息

School of Medicine, Tel Aviv University, Tel-Aviv 69978, Israel.

Internal Medicine A, Shamir Medical Center, Be'er Ya'akov 70300, Israel.

出版信息

J Clin Med. 2024 May 10;13(10):2809. doi: 10.3390/jcm13102809.

Abstract

(1) Crohn's disease (CD) and right-sided colorectal-carcinoma (CRC) are two common indications for right colectomies. Many studies have tried to identify risk factors associated with post-operative complications for both CD and CRC. However, data directly comparing the outcomes of the two are sparse. This study aims to compare the 30-day post-operative outcome after a right colectomy for CD versus CRC. Its secondary aim is to identify the factors associated with these outcomes for each group. (2) A retrospective cohort study of 123 patients who underwent a right colectomy for CD or CRC in a single institution between March 2011 and March 2016. (3) There were no significant differences between the groups when comparing the overall complication rate, the median Clavien-Dindo score, reoperation rates and the length of hospitalization. The leak rate was higher in the Crohn's group (13.95% (6/43) vs. 3.75% (3/80)), = 0.049), although the stoma rate was the same (4/43 9.5%; 7/80 9.9%). (4) This study has shown that post-operative complication rate is similar for right colectomy in CD and CRC. However, Crohn's disease patients did have a higher leak rate.

摘要

(1) 克罗恩病(CD)和右半结肠癌(CRC)是右半结肠切除术的两个常见适应证。许多研究试图确定与CD和CRC术后并发症相关的危险因素。然而,直接比较两者结果的数据很少。本研究旨在比较CD与CRC右半结肠切除术后30天的结果。其次要目的是确定每组与这些结果相关的因素。(2) 对2011年3月至2016年3月期间在单一机构接受CD或CRC右半结肠切除术的123例患者进行回顾性队列研究。(3) 在比较总体并发症发生率、Clavien-Dindo评分中位数、再次手术率和住院时间时,两组之间无显著差异。克罗恩病组的吻合口漏率较高(13.95%(6/43)对3.75%(3/80),P = 0.049),尽管造口率相同(4/43,9.5%;7/80,9.9%)。(4) 本研究表明,CD和CRC右半结肠切除术的术后并发症发生率相似。然而,克罗恩病患者的吻合口漏率确实较高。

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