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青少年分期手术中,术前头环重力牵引与微创临时内部分撑开术治疗重度特发性脊柱侧弯的手术治疗的放射学和肺部结果比较

Radiological and Pulmonary Results of Surgical Treatment of Severe Idiopathic Scoliosis Using Preoperative Halo Gravity Traction Compared with Less Invasive Temporary Internal Distraction in Staged Surgery in Adolescents.

作者信息

Grabala Pawel, Galgano Michael A, Grabala Michal, Buchowski Jacob M

机构信息

Department of Pediatric Orthopedic Surgery and Traumatology, Medical University of Bialystok and Medical University of Bialystok Children's Clinical Hospital, ul. Waszyngtona 17, 15-274 Bialystok, Poland.

Paley European Institute, Al. Rzeczypospolitej 1, 02-972 Warsaw, Poland.

出版信息

J Clin Med. 2024 May 13;13(10):2875. doi: 10.3390/jcm13102875.

Abstract

Severe and rigid scoliosis represents a type of spinal deformity characterized by a Cobb angle exceeding 90° and a flexibility of less than 30%. Halo spinal traction remains the established standard for managing severe scoliosis, although alternative approaches such as temporary internal distraction rods and staged surgical correction exist. The primary objective of this investigation was to compare two cohorts of patients treated using these distinct methods to ascertain any divergences in terms of surgical and radiological outcomes, pulmonary function (PF), and quality of life (QoL). : This study encompassed a total of 62 pediatric patients meeting the specified criteria, which included severe idiopathic scoliosis (major Cobb curve >90) and flexibility <30%. Group 1 (G1) underwent surgical intervention involving preoperative Halo gravity traction (HGT) succeeded by posterior spinal fusion (PSF). On the other hand, Group 2 (G2) underwent a two-stage procedure starting with a less invasive temporary internal distraction technique (LITID) prior to PSF. The radiological outcomes, PF, and QoL were documented and assessed over a monitoring period ranging from 2 to 5 years. The average preoperative major curves (MCs) measured 124° and 122° in G1 and G2, respectively ( < 0.426). Initial flexibility, as observed in preoperative bending films, ranged from 18% in G1 to 21% in G2 ( < 0.001). Following the ultimate surgical intervention, the MCs were corrected to 45° and 37.4° in G1 and G2, respectively ( < 0.001). The percentage correction of the MCs was higher in G2 (63% vs. 70% in G1 and G2, respectively), with significant between-group disparities ( < 0.001). The mean preoperative thoracic kyphoses (TKs) were 96.5° in G1 and 92° in G2 ( = 0.782), which were rectified to 45.8° in G1 and 36.2° in G2 ( < 0.001), equating to correction rates of 55% and 60% in the respective groups. Initially, G2 exhibited lower values for the percentage of predicted lung volume (FVC) and predicted FEV1 compared with G1 (49% and 58% vs. 54.5% and 60.8%; N.S.). Nonetheless, both groups demonstrated enhancements in their FVC and FEV1 values over the follow-up period. The surgical management of severe and untreated spinal curvatures in the pediatric and adolescent population can be considered safe, with a tolerable incidence of minor complications. LITID emerges as a method offering improved QoL and pulmonary function, achieving notably substantial average corrections in deformity by 70% in the coronal plane and 60% in the sagittal plane, alongside a mean increase in trunk height of 10.8 cm. Furthermore, a typical reduction of 76% in rib humps and enhancements in respiratory function, as indicated by improvements in 1 s predicted forced expiratory volume (by 25-56%) and forced vital capacity (by 35-65%), were achieved, leading to a clinically and statistically significant enhancement in QoL when evaluated using SRS-22r, without resorting to more radical, high-risk procedures.

摘要

重度僵硬性脊柱侧凸是一种脊柱畸形,其特征为Cobb角超过90°且柔韧性小于30%。尽管存在诸如临时内部分离棒和分期手术矫正等替代方法,但头环脊柱牵引仍是治疗重度脊柱侧凸的既定标准。本研究的主要目的是比较两组采用不同方法治疗的患者,以确定在手术和放射学结果、肺功能(PF)和生活质量(QoL)方面的任何差异。本研究共纳入62例符合特定标准的儿科患者,这些标准包括重度特发性脊柱侧凸(主要Cobb角>90)和柔韧性<30%。第1组(G1)接受手术干预,包括术前头环重力牵引(HGT),随后进行后路脊柱融合术(PSF)。另一方面,第2组(G2)接受两阶段手术,在PSF之前先采用侵入性较小的临时内部分离技术(LITID)。在2至5年的监测期内记录并评估放射学结果、PF和QoL。G1组和G2组术前平均主要曲线(MCs)分别为124°和122°(P<0.426)。术前弯曲位X线片显示的初始柔韧性,G1组为18%,G2组为21%(P<0.001)。在最终手术干预后,G1组和G2组的MCs分别矫正至45°和37.4°(P<0.001)。G2组MCs的矫正百分比更高(G1组和G2组分别为63%和70%),组间差异显著(P<0.001)。G1组术前平均胸段后凸(TKs)为96.5°,G2组为92°(P =0.782),G1组和G2组分别矫正至45.8°和36.2°(P<0.001),两组矫正率分别为55%和60%。最初,G2组预测肺容积百分比(FVC)和预测第1秒用力呼气容积(FEV1)值低于G1组(分别为49%和58% 对比54.5%和60.8%;无统计学差异)。然而,在随访期间两组的FVC和FEV1值均有所提高。儿童和青少年人群中重度且未经治疗的脊柱侧弯的手术治疗可被认为是安全的,轻微并发症的发生率可耐受。LITID作为一种方法,可改善生活质量和肺功能,在冠状面平均畸形矫正率达70%,矢状面达60%,同时平均躯干高度增加10.8 cm。此外,肋骨隆突通常减少76%,呼吸功能得到改善,如1秒用力呼气容积预测值提高(25%-56%)和用力肺活量提高(35%-65%),使用SRS-22r评估时,生活质量在临床和统计学上有显著提高,且无需采用更激进 的高风险手术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5932/11122294/0399b431ef6c/jcm-13-02875-g001.jpg

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