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医用手套在接触不同溶剂剂时的耐用性:一项体外实验研究。

Medical glove durability during exposure to different solvent agents: an ex-vivo experimental study.

作者信息

Herkins Ashley, Cornish Katrina

机构信息

Department of Food, Agricultural, and Biological Engineering, The Ohio State University, 590 Woody Hayes Drive, Columbus, OH, 43210, USA.

Department of Horticulture and Crop Science, The Ohio State University, 1680 Madison Avenue, Wooster, OH, 44691, USA.

出版信息

Patient Saf Surg. 2024 May 26;18(1):19. doi: 10.1186/s13037-024-00400-4.

Abstract

BACKGROUND

Medical professionals are constantly exposed to bodily fluids and sanitizing agents during routine medical procedures. Unbeknownst to many healthcare workers, however, the barrier integrity of medical gloves can be altered when exposed to these substances, potentially resulting in exposure to dangerous pathogens.

METHODS

This experimental study was designed to test the hypothesis that the durability of both natural and synthetic solvent-exposed medical gloves will be lower than the durability of the gloves in air. The testing consisted of a sample of commercially available medical gloves exposed to 70% ethanol, phosphate buffered saline, and deionized water, aimed at simulating the environments in which medical gloves are commonly worn. Gloves were included in this study based on their performance in previous durability studies in air. Data were collected over a period of three months. The glove assessment device automatically detects pinhole-sized perforations in medical gloves, eliminating the need to visually inspect each glove. Relative durability was measured as the average number of sandpaper touches until glove puncture.

RESULTS

Four out of five glove brands performed better when exposed to all three solvents than in air, which is likely due to slippage in the interface between the wet glove and the sandpaper. Sensicare Micro, a polyisoprene surgical glove, had the most consistent durability in all three solvents tested. A two-way ANOVA revealed that both glove brand (P = 0.0001), solvent (P = 0.0001), and their interaction (P = 0.0040, α = 0.05) significantly affected average glove durability.

CONCLUSIONS

Glove durability did not remain consistent in 70% ethanol, phosphate buffered saline, deionized water, and air. These results make it clear that additional testing and labeling information would help healthcare workers select gloves for use in specific environments to ensure the best barrier protection against disease or toxins.

摘要

背景

在常规医疗程序中,医学专业人员经常接触体液和消毒剂。然而,许多医护人员并不知道,医用手套在接触这些物质时,其屏障完整性可能会改变,从而有可能接触到危险病原体。

方法

本实验研究旨在检验以下假设:天然和合成的接触溶剂的医用手套的耐用性将低于空气中手套的耐用性。测试包括对市售医用手套样本进行70%乙醇、磷酸盐缓冲盐水和去离子水的接触测试,旨在模拟医用手套通常佩戴的环境。根据手套在之前空气中耐用性研究中的表现纳入本研究。数据收集期为三个月。手套评估装置自动检测医用手套上针孔大小的穿孔,无需对每只手套进行目视检查。相对耐用性以手套被刺穿前砂纸摩擦的平均次数来衡量。

结果

五个手套品牌中有四个在接触所有三种溶剂时的表现优于在空气中的表现,这可能是由于湿手套与砂纸之间的界面打滑所致。Sensicare Micro,一种聚异戊二烯手术手套,在所有三种测试溶剂中具有最稳定的耐用性。双向方差分析显示,手套品牌(P = 0.0001)、溶剂(P = 0.0001)及其相互作用(P = 0.0040,α = 0.05)均显著影响手套的平均耐用性。

结论

手套在70%乙醇、磷酸盐缓冲盐水、去离子水和空气中的耐用性并不一致。这些结果表明,额外的测试和标签信息将有助于医护人员选择适合特定环境使用的手套,以确保对疾病或毒素提供最佳屏障保护。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4ed/11129492/db0dc60b8ebe/13037_2024_400_Fig1_HTML.jpg

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