Perlman Susan L
Department of Neurology David Geffen School of Medicine at UCLA Health Sciences 300 UCLA Medical Plaza, Suite B200 Los Angeles, CA 90095, United States.
Clin Park Relat Disord. 2024 May 10;10:100255. doi: 10.1016/j.prdoa.2024.100255. eCollection 2024.
The genetic ataxias have no cures and no proven ways to delay progression (no disease-modifying therapies). The acquired ataxias may have treatments that address the underlying cause and may slow or stop progression, but will not reverse damage already sustained. The idiopathic ataxias (of unknown genetic or acquired cause) also have no proven disease-modifying therapies. However, for all patients with ataxia of any cause, there is always something that can be done to improve quality of life-treat associated symptoms, provide information and resources, counsel patient and family, help with insurance and disability concerns, be available to listen and answer the many questions they will have.
遗传性共济失调无法治愈，也没有经证实的延缓疾病进展的方法（没有疾病修饰疗法）。获得性共济失调可能有针对潜在病因的治疗方法，可能会减缓或阻止疾病进展，但无法逆转已造成的损害。特发性共济失调（病因不明的遗传性或获得性）也没有经证实的疾病修饰疗法。然而，对于所有因任何原因导致共济失调的患者，总有一些事情可以做来改善生活质量——治疗相关症状、提供信息和资源、为患者及其家人提供咨询、帮助解决保险和残疾问题、随时倾听并回答他们会提出的众多问题。
